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[Significance of bone marrow cytology in the diagnosis of leukosis in dogs].
Tierarztl Prax
June 1993
Medizinischen und Gerichtlichen Veterinärklinik I, Lehrstuhl für Innere Krankheiten der Kleintiere, Justus-Liebig-Universität Giessen.
In the differential diagnosis of neoplastic diseases of blood cells or their precursors, cytological examination of bone marrow is a valuable diagnostic tool. Depending on the expected cell type, an aspiration followed by clinical-cytological examination, or a biopsy followed by histopathological examination is indicated. In all unclear cases of cytopenia, if blood parasites or a lymphatic leukemia without tumors are suspected or in myeloproliferative diseases, bone marrow cytology can provide the diagnosis.
View Article and Find Full Text PDFGeneralized lymphosarcomatosis (leukaemia) of non-thymic type occurs in mice bearing 90Sr or 239Pu or 226Ra. Tumours passaged from such mice have been tested for tumour-associated transplantation antigens that could provoke a protective immunity which would be expected if such antigens were determined by virus activated by the irradiation. Sub-threshold doses of living syngeneic tumour, large doses of living allogeneic tumour and large doses of killed syngeneic tumour were without protective effect.
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