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Postoperative Nausea and Vomiting in Pediatrics: Incidence and Guideline Adherence-a Retrospective Cohort Study.
Anesth Analg
November 2024
Department of Anesthesiology, Chaim Sheba Medical Center, Ramat Gan, Israel.
Background: Postoperative nausea and vomiting (PONV) in pediatric patients is a common and clinically significant postoperative complication. The incidence of PONV has not been extensively studied in large pediatric cohorts. Furthermore, in 2020, the Fourth Consensus Guidelines for the management of PONV were published.
View Article and Find Full Text PDFFactors Associated With Decision to Use and Dosing of Sugammadex in Children: A Retrospective Cross-Sectional Observational Study.
Anesth Analg
January 2025
From the Department of Anesthesiology, University of Michigan, Ann Arbor, Michigan.
Background: Sugammadex was initially approved for reversal of neuromuscular blockade in adults in the United States in 2015. Limited data suggest sugammadex is widely used in pediatric anesthesia practice however the factors influencing use are not known. We explore patient, surgical, and institutional factors associated with the decision to use sugammadex versus neostigmine or no reversal, and the decision to use 2 mg/kg vs 4 mg/kg dosing.
View Article and Find Full Text PDFNeuromuscular Blockade Reversal with Sugammadex Reduces Cardiac Complications and OR Time for Prone Lumbar Spinal Fusion Compared to Neostigmine.
Spine (Phila Pa 1976)
December 2024
Brown University Department of Orthopaedic Surgery, Providence, Rhode Island.
Study Design: Retrospective cohort study.
Objective: To evaluate inpatient complication profiles of patients receiving neuromuscular blockade reversal via sugammadex versus neostigmine/glycopyrrolate.
Summary Of Background Data: Sugammadex is a neuromuscular blockade reversal agent that binds non-depolarizing muscle relaxants.
The Efficacy and Adverse Effects of Sugammadex and Neostigmine in Reversing Neuromuscular Blockade Inpatients with Obesity Undergoing Metabolic and Bariatric Surgery: A Systematic Review with Meta-Analysis and Trial Sequential Analysis.
Medicina (Kaunas)
November 2024
Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu 610041, China.
Article Synopsis
- Metabolic and bariatric surgery (MBS) is used globally, and this study explores the benefits of sugammadex in reversing neuromuscular blockade (NMB) for obese patients undergoing the procedure, comparing it to neostigmine.*
- The systematic review analyzed data from nine studies involving 633 patients, finding that sugammadex led to significantly quicker recovery times and reduced risks of postoperative complications like residual curarization, nausea, vomiting, and cardiovascular issues.*
- The findings suggest that sugammadex is a more effective and safer option than neostigmine for managing NMB in obese patients during bariatric surgeries.*
Deadly Nightshade (Atropa belladonna) and Other Weed Poisonings in the Pediatric Intensive Care Unit: Analysis of 54 Children.
Turk Arch Pediatr
November 2024
T. C. University of Health Sciences, Van Training and Research Hospital, Pediatrics Clinic, Van, Türkiye.
Article Synopsis
- The study focused on analyzing cases of poisoning from Atropa belladonna (deadly nightshade) among children, reviewing records from January 2010 to January 2022.
- Out of 54 children admitted for poisoning, 24 (44.4%) cases were due to deadly nightshade, presenting symptoms like flushing, vomiting, and severe cases requiring mechanical ventilation.
- The research highlighted key differences in symptom severity between deadly nightshade and other weed poisonings, with significant effects on ICU stay duration and respiratory support needs, yet no fatalities were reported.
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