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Impact of hospital formulary intervention on carbapenem use: a segmented time-series analysis of consumption and a propensity score-matched non-inferiority study of treatment efficacy.
J Pharm Health Care Sci
January 2025
Laboratory of Clinical Pharmacy Education, Research and Education Center for Clinical Pharmacy, School of Pharmacy, Kitasato University, 5-9-1, Shirokane, Minato-ku, Tokyo, 108-8641, Japan.
Background: Pharmaceutical formularies play a crucial role in guiding medication use by balancing clinical effectiveness and cost efficiency. Although formulary implementation has been increasing in Japan, comprehensive evaluations of its impact on both clinical and economic outcomes are limited. This study aimed to assess the effect of introducing an antimicrobial formulary at Yokohama City University Hospital on antibiotic usage and treatment outcomes in intra-abdominal infections.
View Article and Find Full Text PDFAre medical school preclinical tests biased for sex and race? A differential item functioning analysis.
BMC Med Educ
January 2025
University of Minnesota Medical School, 420 Delaware Street SE, Mayo Building, Minneapolis, MN, 55455, USA.
Background: A common practice in assessment development, fundamental for fairness and consequently the validity of test score interpretations and uses, is to ascertain whether test items function equally across test-taker groups. Accordingly, we conducted differential item functioning (DIF) analysis, a psychometric procedure for detecting potential item bias, for three preclinical medical school foundational courses based on students' sex and race.
Methods: The sample included 520, 519, and 344 medical students for anatomy, histology, and physiology, respectively, collected from 2018 to 2020.
The association between 24-h movement behaviours and adiposity among Australian preschoolers: a compositional data analysis.
BMC Public Health
January 2025
Early Start, Faculty of the Arts, Social Sciences and Humanities, University of Wollongong, Wollongong, NSW, 2522, Australia.
Introduction: The relationship between 24-h movement behaviours (i.e. sleep, sedentary behaviour and physical activity) and adiposity in preschoolers remains unclear.
View Article and Find Full Text PDFDigital Motherhood in the Postpartum Period: A Descriptive Study.
Matern Child Health J
January 2025
Department of Public Health Nursing, Department of Nursing, Faculty of Health Science, Pamukkale University, Pamukkale, Campus Denizli, 20160, Turkey.
Background: During the first 6 weeks after birth, women often encounter problems and seek answers to their questions. This period is also crucial in terms of technology use.
Aim: The aim of this study was to examine the digital motherhood approach to self-care and infant care in the 6-week postpartum period, and its association with different variables.
Comparative effectiveness, safety and persistence of ocrelizumab versus natalizumab in multiple sclerosis: A real-world, multi-center, propensity score-matched study.
Neurotherapeutics
January 2025
Department of Human Neurosciences, Sapienza University, Rome, Italy. Electronic address:
Ocrelizumab (OCR) and Natalizumab (NTZ) are highly effective treatments widely used in Multiple Sclerosis (MS). However, long-term, real-world comparative data on clinical effectiveness, safety and treatment persistence are limited. This retrospective analysis included relapsing and progressive MS patients initiating treatment at two Italian Universities ("La Sapienza" and "Federico II").
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