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The management of locally advanced esophageal cancer typically involves esophagectomy; however, postoperative complications, particularly anastomotic stricture, remain prevalent. Anastomotic stricture can severely compromise patients' quality of life by leading to difficulties in food intake. Although endoscopic balloon dilation has become a standard treatment for gastrointestinal strictures, its efficacy is often limited due to the risk of perforation and the potential for recurrent stricture, necessitating multiple interventions.
View Article and Find Full Text PDFAAPM Task Group Report 274: Fluence rate dosimetry for photodynamic therapy (PDT).
Med Phys
January 2025
Netherlands Cancer Institute - Antoni van Leeuwenhoek hospital, NKI-AvL, Amsterdam, Netherlands.
Photodynamic therapy (PDT) is a treatment modality clinically approved for several oncologic indications, including esophageal and endobronchial cancers, precancerous conditions including Barrett's esophagus and actinic keratosis, and benign conditions like age-related macular degeneration. While it is currently clinically underused, PDT is an area of significant research interest. Because PDT relies on the absorption of light energy by intrinsic or administered absorbers, the dosimetric quantity of interest is the absorbed energy per unit mass of tissue, proportional to the fluence rate of light in tissue.
View Article and Find Full Text PDFA Rare Case of Dysphagia: A Case Report.
Euroasian J Hepatogastroenterol
December 2024
Department of Histopathology, AKUH Hospital, Karachi, Sindh, Pakistan.
Unlabelled: Esophageal leiomyomas (EL) are the most common benign tumors of the esophagus, being pedunculated polyp presentation is very rare. A 65-year-old female presented with symptoms of troublesome dysphagia. Esophagogastroduodenoscopy (EGD) performed revealed a pedunculated polyp of ~ 3 × 1.
View Article and Find Full Text PDFThe A to Z of Peroral Endoscopic Myotomy.
J Clin Gastroenterol
February 2025
Digestive Disease and Surgery Institute, Cleveland Clinic London, UK.
Peroral endoscopic myotomy (POEM) is a novel technique within the field of third space endoscopy. The overarching principal is creation of a mucosal incision, careful dissection of the submucosal space using an electrosurgical knife to reach the muscularis (ie, tunneling), performing a controlled myotomy, and finally, closure of the mucosal incision. POEM was first developed for the management of achalasia, and now a decade of evidence shows the procedure is safe, effective, and highly reproducible.
View Article and Find Full Text PDFUnusual presentation of esophageal tuberculosis: a case study.
BMC Infect Dis
January 2025
Department of Radiation Oncology, Cancer Treatment Center, The Second Affiliated Hospital of Hainan Medical University, 368 Yehai Road, Haikou, 570311, China.
Background: Esophageal ulcers can arise not only from malignant lesions but also from benign diseases, such as tuberculosis. These ulcers may mimic the radiological features of esophageal malignancy or tuberculosis on PET/CT, leading to diagnostic challenges.
Case Presentation: A 59-year-old woman was admitted to our hospital with a month-long history of progressive painful swallowing, fatigue, and loss of appetite.
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