Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Simultaneous triple peptic perforations: a report of an extremely rare case.
J Surg Case Rep
January 2025
Faculty of Medicine, Can Tho University of Medicine and Pharmacy, 179 Nguyen Van Cu Street, An Khanh Ward, Ninh Kieu District, Can Tho 900000, Vietnam.
Peptic ulcer perforations are common in surgical emergencies, whereas double perforations are rare, and triple peptic perforations are even exceedingly rare, with only a few cases documented. While undetected perforation during surgery can be fatal, the absence of standardized procedures for managing multiple perforations remains an ongoing challenge for surgeons. Herein, we describe a rare case of simultaneous triple peptic perforations in an elderly man with a prolonged history of analgesic and corticosteroid use.
View Article and Find Full Text PDFTrends in Proton Pump Inhibitor Use in Sweden by Sex and Age: A Drug Utilisation Study.
Drug Saf
December 2024
Department of Women's and Children's Health, Karolinska Institutet, Tomtebodavägen 18A, 17177, Stockholm, Sweden.
Background: Proton pump inhibitors (PPIs) are among the most popular drugs worldwide. Yet, there are concerns on long-term safety and poor adherence to prescription guidelines. Off-label use in children and increasing maintenance use in older adults may be particularly worrisome.
View Article and Find Full Text PDFTunnel anastomosis: a modified flap technique in esophagogastrostomy as a novel antireflux technique after proximal gastrectomy.
J Gastrointest Surg
January 2025
Department of General Surgery, The Affiliated Cancer Hospital of Nanjing Medical University & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Nanjing, Jiangsu, China. Electronic address:
Background: The prevalence of proximal gastric cancer (PGC) has been increasing rapidly worldwide. Postoperative reflux esophagitis after conventional esophagogastrostomy (EG) is a major problem that haunts surgeons. This study designed a novel antireflux technique called tunnel anastomosis in EG after proximal gastrectomy (PG).
View Article and Find Full Text PDF[Evaluation of esophagogastric anastomosis with additional mechanical anti-reflux barrier after proximal gastrectomy].
Zhonghua Wei Chang Wai Ke Za Zhi
October 2024
Department of General Surgery, Second Affiliated Hospital of Air Force Military Medical University, Xi'an 710038, China.
Article Synopsis
- The use of proximal gastrectomy for upper gastric cancer and esophagogastric junction (AEG) patients is on the rise due to advances in function-preserving surgery techniques.
- Issues like postoperative reflux esophagitis and anastomotic stenosis have become major concerns as these surgeries increase in frequency.
- Researchers have developed various esophagogastric reconstruction methods to minimize reflux, but there is still no consensus on the ideal technique, highlighting the need for further exploration and understanding in this area.
Global Transcriptomic Analysis of Topical Sodium Alginate Protection against Peptic Damage in an In Vitro Model of Treatment-Resistant Gastroesophageal Reflux Disease.
Int J Mol Sci
October 2024
Department of Otolaryngology and Communication Sciences, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Breakthrough symptoms are thought to occur in roughly half of all gastroesophageal reflux disease (GERD) patients despite maximal acid suppression (proton pump inhibitor, PPI) therapy. Topical alginates have recently been shown to enhance mucosal defense against acid-pepsin insult during GERD. We aimed to examine potential alginate protection of transcriptomic changes in a cell culture model of PPI-recalcitrant GERD.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!