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A novel proceduralized donor liver back-table preparation technique minimizes hemorrhage following liver implantation in orthotropic liver transplantation.
Front Surg
December 2024
Hepatopancreatobiliary Center, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Institute for Precision Medicine, Tsinghua University, Beijing, China.
Background: Intraoperative hemorrhage is one of the major complications of orthotopic liver transplantation (OLT) and is mainly caused by technical difficulties of the surgical procedure besides primary liver diseases. The present study aimed to evaluate the feasibility and clinical effects of a novel proceduralized donor liver back-table preparation (DLBTP) technique for use in OLT.
Methods: This retrospective study was conducted between January 2018 and June 2020 based on patients who had undergone OLT.
A Systematic Review of Current Practices, Challenges, and Future Directions for the Use of Robotic Surgery in Otolaryngology in Greece.
Cureus
November 2024
Hellenic Minimally Invasive and Robotic Surgery (MIRS) Study Group, Medical School, National and Kapodistrian University of Athens, Athens, GRC.
Robotic surgery is increasingly used in otolaryngology (ENT), particularly for complex head and neck procedures. It offers various advantages, including limited postoperative pain, excellent aesthetic results, better visualization in the surgical field, enhanced dexterity due to movement adjustment by the robotic system, and minimal complications and hospital stay. However, robotic systems' higher cost and limited availability are a burden for clinical applications.
View Article and Find Full Text PDFUncommon but Significant: Onset, Characteristics and Management of Vasculitis and Connective Tissue Diseases Induced by Immunomodulators during Cancer Treatment.
Discov Med
December 2024
Department of Ophthalmology, University Hospital of Udine, 33100 Udine, Italy.
The introduction of immunomodulators as adjuvant therapies in cancer treatment has represented a significant advancement in oncology, improving therapeutic response and patient survival. Emerging targets and molecules could provide new therapeutic opportunities for cancer patients. However, these agents can induce immunological side effects, including vasculitis and connective tissue diseases, which, while uncommon, present significant clinical challenges.
View Article and Find Full Text PDFCorrelating GC/MS Relative Response Factors to Analyte's Physicochemical and Chromatographic Properties to Facilitate the Quantitation of Organic Extractables and Leachables in Non-Targeted Analysis (NTA). Concepts and Empirical Considerations.
PDA J Pharm Sci Technol
December 2024
Nelson Labs, Romeinsestraat 12, 3001 Heverlee, Belgium.
Leachables in drug products and from medical devices can adversely affect patient health and thus must be identified and quantified. Accurate and protective quantitation in target analysis for leachables (and extractables as potential leachables) is accomplished via compound-specific calibration curves. Quantification in non-targeted analysis (NTA) is complicated by the variable relative response factors (RRFs) among and between individual leachables and the circumstance that the leachables are not known until the NTA is completed.
View Article and Find Full Text PDFFeasibility and Safety of Double-wire Technique for Microcatheter Navigation Beyond Tortuous Internal Carotid Siphon: a Propensity Score Matched Study.
World Neurosurg
December 2024
Department of Neurosurgery, The Jikei University School of Medicine, Tokyo, Japan.
Background: Severe vessel tortuosity may prevent a microcatheter from reaching a distal vessel. However, the Double-Wire Technique (DWT) may facilitate the procedure. The present study evaluated the feasibility and safety of guiding a 0.
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