Ecology plays more and more important role as an etiological factor of human diseases: congenital defects, tumours, immunodyzergies, hematopoietic and endocrine disorders. Two directions should be taken into consideration in establishing the role of ecology in human disease: pathology itself and ecogenic factor. The first one consists of the complex "populations at risk-pattern of mortality-ecogenic diseases, the second direction is "geography of potentially ecogenic diseases-correlation with geography of environmental pollution-eco-etiological factor". The analysis of death causes may form an alternative to generalized ecomedical analysis having a low informative value. Additional problem of ecological pathology is an ecogenically induced weakness, premorbid and latent states.

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