Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Development of a riboflavin-responsive model of riboflavin transporter deficiency in zebrafish.
Hum Mol Genet
December 2024
Children's Hospital of Eastern Ontario Research Institute, 401 Smyth Road, Ottawa K1H 8L1, Canada.
Riboflavin transporter deficiency (RTD) is a rare and progressive neurodegenerative disease resulting from the disruption of RFVT2- and RFVT3- mediated riboflavin transport caused by biallelic mutations in SLC52A2 and SLC52A3, respectively. The resulting impaired mitochondrial metabolism leads to sensorimotor neurodegeneration and symptoms including muscle weakness, respiratory difficulty, and sensorineural deafness. Although over 70% of patients with RTD improve following high-dose riboflavin supplementation, remaining patients either stabilise or continue to deteriorate.
View Article and Find Full Text PDFTryptophan Metabolism-Regulating Probiotics Alleviate Hyperuricemia by Protecting the Gut Barrier Integrity and Enhancing Colonic Uric Acid Excretion.
J Agric Food Chem
December 2024
College of Food Science and Engineering, Northwest A&F University, Yangling 712100, China.
The balance of gut microbiota affects uric acid synthesis and excretion, influencing the development of hyperuricemia. This study aimed to investigate the effects and mechanisms of probiotics on hyperuricemia and adenine- and potassium oxonate-induced colonic damage. After two months of gavage at 10 CFU/day, the probiotic strains UA260 and YU28, identified through screening, significantly reduced serum uric acid levels in hyperuricemia mice from 109.
View Article and Find Full Text PDFMetabolomic Prediction of Cadmium Nephrotoxicity in the Snail .
Metabolites
August 2024
Laboratory of Human Biology & Toxicology, Faculty of Medicine and Pharmacy, University of Mons, 7000 Mons, Belgium.
The decontamination of polluted soils is a major socioeconomic issue in many industrialized countries. In situ remediation approaches are nowadays preferred to ex situ techniques, but they require among others the use of bioindicators, which are sensitive to the progressive depollution on health effects. Animal species have been mainly used so far to monitor aquatic and air pollution.
View Article and Find Full Text PDF[Influence of chronic immobilization stress on vitamin status in rats fed different diets].
Vopr Pitan
April 2024
Federal Research Centre of Nutrition, Biotechnology and Food Safety, 109240, Moscow, Russian Federation.
The influence of a stress factor, widespread in modern conditions, on the vitamin status has not been studied enough. At the same time, the negative stress impact can be aggravated against the background of unhealthy nutrition, which in turn affects the vitamin status of the organism. In this regard, of the research was to evaluate the effect of chronic restrict stress on the vitamin supply in rats fed a diet with adequate and increased content of fat, sugar and cholesterol.
View Article and Find Full Text PDF[Influence of the rat diet enrichment with oat β-gucans on the assimilation of B group vitamins, mineral elements and lipid metabolism].
Vopr Pitan
April 2024
Siberian State Medical University, Ministry of Health of the Russian Federation, 634050, Tomsk, Russian Federation.
Article Synopsis
- The study aimed to investigate how oat bran rich in β-glucans affects the absorption of vitamins and minerals, particularly in rats with deficiencies in vitamins D, B group, and trace elements like iron, copper, and zinc.
- After a period of 23 days inducing micronutrient deficiencies, rats were given a semi-synthetic diet supplemented with missing micronutrients for 7 days, with some groups also receiving β-glucans.
- Results showed that replenishing vitamins B1, B2, and B6 eliminated deficiencies, while β-glucans enhanced iron absorption, evidenced by increased plasma iron levels and decreased urinary iron excretion.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!