The theory of granulocyte embolization in the retinal arterioles in acute pancreatitis cannot account for several aspects of the ophthalmic complication. Therefore we studied retinal circulation by fluorescein angiography, light and transmission electron microscopy following the first six hours of acute experimental necrotizing pancreatitis. The studied period was characterized by high serum lipase and amylase concentrations, hypocalcemia, necrosis of the pancreatic tissue and preceded the development of hypovolemic shock. Ophthalmoscopy and fluorescein angiography revealed no pathologic alterations and no granulocyte aggregation was found. Our results suggest that granulocyte aggregation induced by pancreatic enzymes is not the reason for the ophthalmic circulatory disturbances in acute pancreatitis.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/j.1755-3768.1992.tb04894.x | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Chronic Use of Proton Pump Inhibitors Is Associated With Reduced 30-Day Mortality From Acute Pancreatitis.
Aliment Pharmacol Ther
January 2025
Department of Gastroenterology, Rambam Health Care Campus, Haifa, Israel.
Proton pump inhibitors (PPIs) decrease pancreatic exocrine secretions. There has been interest in the impact of their short-term in-hospital administration on acute pancreatitis (AP) outcomes. It is unknown whether long-term use affects AP outcomes.
View Article and Find Full Text PDFUnraveling the Microenvironment and the Pathogenic Axis of HIF-1α-Visfatin-Fibrosis in Autoimmune Pancreatitis Using a Single-Cell Atlas.
Adv Sci (Weinh)
January 2025
Department of Gastroenterology, Changhai Hospital, Shanghai, 200433, China.
Autoimmune pancreatitis (AIP) is identified as a severe chronic immune-related disorder in pancreas, including two subtypes. In this study, pancreatic lesions in patients diagnosed as either type 1 AIP or type 2 AIP are examined, and these patients' peripheral blood at single-cell level. Furthermore, flow cytometry, immunofluorescence, and functional assays are performed to verify the identified cell subtypes.
View Article and Find Full Text PDF[Exercise therapy in outpatient rehabilitation programmes for patients with comorbid digestive pathology in colon cancer and chronic pancreatitis. (Open randomized controlled trial)].
Vopr Kurortol Fizioter Lech Fiz Kult
January 2025
Federal Centre for Brain and Neurotechnology of Federal Medical and Biological Agency, Moscow, Russia.
Unlabelled: Sanogenetic effects of physical factors that have an activating effect on the adaptation-compensatory mechanisms of the body are known. On the other hand, their comparative effect on the pathogenetic links of the disease has been proven. It is advisable to use them in comorbid pathology of the digestive system to increase the effectiveness of rehabilitation measures.
View Article and Find Full Text PDFObjectives: Endoscopic ultrasonography (EUS)-guided radiofrequency ablation has recently been introduced as one of the management strategies for small pancreatic neuroendocrine neoplasms (PNENs). However, prospective data on its safety and efficacy remain limited.
Methods: This prospective pilot study was conducted at Okayama University Hospital from May 2023 to December 2024.
Patient outcomes and health care resource utilization in acute pancreatitis-related central nervous system complications: insights from a national cohort study.
J Int Med Res
January 2025
Department of Gastroenterology and Hepatology, Henry Ford Hospital, Detroit, MI, United States.
Objectives: Central nervous system complications of acute pancreatitis (AP) can result in cerebral edema (CE). We assessed the risk of serious outcomes and health care features associated with CE in patients hospitalized with AP.
Methods: We conducted a retrospective cohort study using the National Inpatient Sample database.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!