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Handedness.
Handb Clin Neurol
March 2025
Institute of Cognitive Neuroscience, Ruhr University Bochum, Bochum, Germany; Research Center One Health Ruhr, Research Alliance Ruhr, Ruhr University Bochum, Bochum, Germany.
This chapter offers an overview of the literature on human handedness and its assessment in clinical neurologic practice and research. There are two major forms of handedness: hand preference, which describes a subjective preference to use one hand over the other for skilled motor activities like writing, and hand skill, which describes objectively measured mother skill. This chapter gives an overview of widely used questionnaires and tests to assess hand preference and hand skill, as well as suggestions on how to determine handedness categories such as left-handed, right-handed, and mixed-handed based on the results of these questionnaires and tests.
View Article and Find Full Text PDFSynergistic antibacterial effects of pinaverium bromide and oxacillin against .
Zhong Nan Da Xue Xue Bao Yi Xue Ban
October 2024
Department of Laboratory Medicine, Third Xiangya Hospital, Central South University, Changsha 410013, China.
Objectives: () adheres to the surface of medical devices, forming highly drug-resistant biofilms, which has made the development of novel antibacterial agents against and its biofilms a key research focus. By drug repurposing, this study aims to explore the combinational antimicrobial effects between pinaverium bromide (PVB), a -type calcium channel blocker, and oxacillin (OXA) against .
Methods: Clinical isolates of were collected from January to September 2022 at the Department of Clinical Laboratory of the Third Xiangya Hospital, Central South University.
Outcome measurement for gender-affirming care in Canada: a systematic review.
BMJ Open
March 2025
Department of Orthopaedics Rheumatology and Musculoskeletal Sciences, University of Oxford Nuffield, Oxford, UK
Introduction: Gender-affirming care (GAC) includes interventions aimed at supporting an individual's gender identity. Canada is experiencing an increase in referrals for GAC, higher than any other health service; therefore, there is a need for a systematic approach to health outcome measurement to effectively evaluate care. This review aims to analyse health outcome measurement in Canadian GAC, focusing on what is measured, how it is measured and associated barriers and enablers.
View Article and Find Full Text PDFEvaluating multifaceted strategies to prevent nasoenteral tube complications and achieve significant cost savings in critically ill patients: the ENHANCE-CRIT trial.
BMJ Open Qual
March 2025
Enteral and Parenteral Nutrition Team, Hospital Israelita Albert Einstein, Sao Paulo, Brazil
Background: Nasoenteral tube (NET) use is common in critically ill patients but is associated with significant complications, including accidental dislodgement, malpositioning in the bronchial tree or mechanical failures, which can impede nutritional therapy. These complications often lead to adverse events that increase hospital stay, costs, and patient morbidity.
Objective: This study aimed to reduce complications related to the placement and maintenance of NETs in critically ill patients using multifaceted strategies.
The Multifaceted Role of CS1 (SLAMF7) in Immunoregulation: Implications for Cancer Therapy and Autoimmune Disorders.
Exp Cell Res
March 2025
Central Labs, King Khalid University, AlQura'a, Abha, Saudi Arabia; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia. Electronic address:
CS1 (SLAMF7), a pivotal immune receptor, plays a dual role in modulating immune responses in autoimmune diseases and cancer. In autoimmunity, aberrant CS1 signaling contributes to the activation of autoreactive lymphocytes, driving pathologies such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). Conversely, in oncology, CS1 serves as a promising immunotherapeutic target, exemplified by the efficacy of the monoclonal antibody Elotuzumab in multiple myeloma.
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