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Background: To assess the clinical utility of PCA3 in the diagnostic accuracy, the correlation between PCA3 and biopsy or pathological characteristics and the performance of PCA3 to reduce the unnecessary biopsies in Chinese population.

Methods: A prospective study including patients with indication of prostate biopsies from 4 centers was conducted. All patients underwent PCA3 urine tests and prostate biopsies.

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Objectives: To evaluate the efficacy of artificial urinary sphincter (AUS) implantation in men with stress urinary incontinence post-radical prostatectomy and the complication burden with a focus on identifying potential risk factors for reoperation as well as determining the fate of revision surgeries.

Methods: Retrospective analysis of consecutive patients undergoing primary AUS (pAUS) and revision AUS (rAUS) implantation at a tertiary centre. Logistic regression was employed to identify risk factors for reoperation associated with non-mechanical failures.

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This editorial highlights the importance of catheterisation documentation and the practice of trials without catheters in improving patient outcomes in Pakistan. Acute urinary retention, a major urological emergency, needs short-term catheter placement, with a trial without a catheter used globally to reduce catheter-associated urinary tract infections. This procedure, often enhanced by alpha-1 blockers, enables patients to regain continence and promotes micturition post-catheterisation, particularly useful following surgeries such as prostatectomy.

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Article Synopsis
  • There was an increased risk of positive resection margins (RMs) in patients who underwent robotic-assisted laparoscopic radical prostatectomy (RARP) after having systematic prostate biopsies.
  • The study evaluated 61 patients who had MRI-ultrasonography fusion and systematic biopsies, and found that the RM-positive group generally had a higher clinical stage and a greater proportion of positive biopsy results.
  • Logistic regression indicated that the positivity rate of systematic biopsies was a significant risk factor for RM positivity, suggesting that these biopsies might be important for assessing the feasibility of preserving the neurovascular bundles during surgery.
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Holmium laser enucleation of the prostate (HoLEP) and robot-assisted simple prostatectomy (RASP) have emerged as the two surgical treatments of medication-refractory benign prostatic hyperplasia (BPH). The comparative outcomes of en-bloc HoLEP with early apical release and RASP with modified Freyer's technique remain unexplored. Between 2018 and 2022, patients with medication-refractory BPH and prostate volume ≥80 g underwent HoLEP or RASP depending on clinical characteristics, patient choice, and surgeon preference.

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