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Melioidosis rarely presents with spinal involvement, which may lead to neurological complications. It's endemic to Thailand and Australia, but rare in India. Patients with diabetes, immunocompromised states, and chronic renal failure are at high risk of developing melioidosis, which can present with localized or disseminated abscess collection.

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Abscesses due to Melioidosis: A case-based review.

Curr Res Microb Sci

November 2024

Department of Microbiology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal 576104, India.

Melioidosis is caused by percutaneous inoculation or inhalation of , predominantly among individuals with risk factors (diabetes mellitus, immunosuppression, etc.) from endemic areas of South Asia, Southeast Asia and Northern Australia. While some patients present acutely with sepsis and multi-organ failure, others present with a subacute to chronic course characterised by abscess formation.

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Article Synopsis
  • Melioidosis is a serious tropical infection with limited understanding of how it affects the mediastinum, leading to a study that aimed to categorize its radiological features and assess patient demographics.
  • A retrospective analysis of CT scans from 70 out of 486 melioidosis patients identified 41 with mediastinal involvement, revealing diverse morphological presentations including necrotic lymph nodes and fluid collections.
  • Half of the patients had diabetes, and the study suggests that further research is needed to understand the implications of these findings and the prognosis of mediastinal melioidosis.
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Melioidosis is caused by community-acquired gram-negative bacillus which resides in soil and water. It was first described in 1912 in Burma and 1927 in Sri Lanka. Melioidosis presents with non-specific clinical and biochemical findings.

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Background We studied the clinical features and treatment outcome of patients with melioidosis in our hospital. Methods We did this retrospective observational chart review over a period of 7 years between December 2014 and February 2022. Results There were 59 cases and 23 deaths attributable to melioidosis over the study period.

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