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CONGENITAL HYPOTHYROIDISM SCREENING RESULTS IN THE TURKISH PROVINCE OF ADIYAMAN IN 2015-2020.
Acta Endocrinol (Buchar)
January 2025
Adıyaman Training and Research Hospital, Department of Pediatric Endocrinology, Adıyaman, Turkey.
Context: Congenital hypothyroidism (CH) is one of the most common preventable causes of intellectual disability, and can be diagnosed in the early period through neonatal screening programs.
Objective: The purpose of this study was to determine the prevalence of CH and recall rates in the province of Adıyaman.
Design: This retrospective study evaluated the data of newborn screening program in Adıyaman province between January 2015 and December 2020.
Comparison of external calibration and isotope dilution methods for iodine determination in foods by inductively coupled plasma mass spectrometry.
Food Chem X
January 2025
Institute of Nutrition, Mahidol University, Salaya, Phuthamonthon, Nakhon Pathom 73170, Thailand.
This study sought to validate the external calibration curve (CAL) method for iodine analysis in 26 selected foods and then to compare the test result with the isotope dilution mass spectrometry (IDMS). Iodine was extracted by tetramethylammonium hydroxide (TMAH) and determined by ICP-MS using CAL and IDMS methods. The results showed that iodine determination using the IDMS method had higher precision than the CAL method (LOD of the method were 0.
View Article and Find Full Text PDF[Vacuum ultraviolet laser dissociation and proteomic analysis of halogenated peptides].
Se Pu
February 2025
CAS Key Laboratory of Separation Sciences for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.
Chemical modifications are widely used in research fields such as quantitative proteomics and interaction analyses. Chemical-modification targets can be roughly divided into four categories, including those that integrate isotope labels for quantification purposes, probe the structures of proteins through covalent labeling or cross-linking, incorporate labels to improve the ionization or dissociation of characteristic peptides in complex mixtures, and affinity-enrich various poorly abundant protein translational modifications (PTMs). A chemical modification reaction needs to be simple and efficient for use in proteomics analysis, and should be performed without any complicated process for preparing the labeling reagent.
View Article and Find Full Text PDFHarnessing Radionuclides: Unveiling the Promising Role of Radiopharmaceuticals in Cancer Theranostics and Palliative Care.
Curr Radiopharm
January 2025
Apollonia" University of Iasi, Faculty of Dental Medicine, 11 Pacurari Str., 700511, Iasi, Romania.
Background: In the context of modern oncology, radiogenic elements have emerged as pivotal tools for targeted cancer therapies. Elements like Iodine-131 and Yttrium-90 offer unique radiological properties that allow precise treatment delivery. This article explores their growing importance and potential in reshaping the landscape of cancer therapy.
View Article and Find Full Text PDFThe Role of the Parametric Thyroid Feedback Quantile Index in Cardiovascular Risk Evaluation Among Euthyroid Koreans.
J Clin Endocrinol Metab
January 2025
Department of Internal Medicine, Hallym University Dongtan Sacred Heart Hospital, Gyeonggi-do, 18450, South Korea.
Context: Thyroid hormones play a crucial role in metabolic regulation and maintaining cardiovascular homeostasis. The Parametric Thyroid Feedback Quantile-based Index (PTFQI) assesses central thyroid hormone sensitivity by standardizing the inverse relationship between free thyroxine (T4) and thyroid-stimulating hormone (TSH).
Objective: To investigate the relationship between PTFQI and cardiovascular risk in the euthyroid Korean population.
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