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Article Synopsis
  • Biomagnetic fluid dynamics (BFD) focuses on the behavior of bio-fluids, like blood, impacted by magnetic fields, which is important for medical applications such as targeted medication delivery and tumor treatment.
  • This study examines blood flow dynamics using trihybrid nanoparticles in a catheterized artery, factoring in various electromagnetic influences and propulsion mechanisms.
  • Key findings include that increasing Hall and ion-slip parameters boosts blood velocity, modifies entropy generation, and shows that modified hybrid nano-blood forms smaller, more manageable clumps compared to pure blood, with longer cilia enhancing recovery of these clumps.
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Adult Phenotype of -Associated Disorders.

Neurol Genet

December 2024

From the Institute of Medical Science (M.R.), University of Toronto; Adult Genetic Epilepsy (AGE) Program (M.R., Q.Z.A., F.Q., I.C., A.A., D.M.A.), Krembil Neurosciences Institute, Toronto Western Hospital, University Health Network, Canada; Epilepsy Unit (A.A.-S.), Vithas Clinical Neuroscience Institute, Vithas Madrid University Hospitals; Faculty of Experimental Sciences (A.A.-S.), Francisco de Vitoria University, Madrid, Spain; Department of Drug Design and Pharmacology (A.B.), University of Copenhagen; Department for Genetics and Personalized Medicine (A.B.), Danish Epilepsy Centre, Dianalund; Institute for Regional Health Services (A.B.), University of Southern Denmark, Odense; NYU Langone Epilepsy Center (O.D., F.Q., A.A.); Edmond J. Safra Program in Parkinson's Disease (A.F.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN; Division of Neurology (A.F., D.M.A.), Department of Medicine, University of Toronto; Krembil Brain Institute (A.F., D.M.A.); Clinical Genetics Research Program (A.S.B.), Centre for Addiction and Mental Health; The Dalglish Family 22q Clinic (A.S.B.), Toronto General Hospital, University Health Network; Department of Psychiatry (A.S.B.), University of Toronto, Ontario; Toronto Congenital Cardiac Centre for Adults (A.S.B.), Division of Cardiology, Department of Medicine, and Department of Psychiatry, University Health Network and Toronto General Hospital Research Institute and Campbell Family Mental Health Research Institute (A.S.B.), Toronto, Ontario, Canada.

Background And Objectives: Pathogenic variants are associated with neurodevelopmental disorders and developmental and epileptic encephalopathy. While pediatric phenotypes have been readily explored, adult phenotypes are not well understood. We aimed to investigate the phenotypic spectrum of adult patients with variants.

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Article Synopsis
  • Port-wine stains (PWS) are vascular birthmarks that can darken over time, and traditional treatments like laser therapy have mixed results and side effects.
  • Hematoporphyrin Monomethyl Ether-Photodynamic Therapy (HMME-PDT) is a new approach showing promising results with fewer adverse effects by specifically targeting abnormal blood vessels.
  • The review highlights the clinical effectiveness of HMME-PDT based on assessments, notes improvements in vascular lesions, and calls for further research to establish consistent treatment guidelines and long-term outcomes.
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Unusual oral manifestation of Kindler syndrome: a case report and review of literature.

Front Oral Health

September 2024

Department of Oral and Maxillofacial Surgery, A B Shetty Memorial Institute of Dental Sciences, Nitte (Deemed to be University), Deralakatte, India.

Article Synopsis
  • Kindler syndrome (KS) is a rare skin condition that starts in babies and causes painful blisters, unusual skin color changes, and sensitivity to sunlight as they get older.
  • It happens because of a problem with a protein called kindlin-1, which helps skin cells stick together and move properly.
  • People with KS can have issues with their mouths that are often missed or treated wrong, and having diabetes can make these problems worse, leading to bigger challenges with healing and skin issues.
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Article Synopsis
  • A young anemic woman developed liver failure and swelling after taking ferrous sulfate, leading to the discovery of her congenital erythropoietic porphyria (CEP) through a skin exam and lab tests.
  • She received treatment that included IV methylprednisolone, blood transfusions, vitamins, and wound care.
  • The report highlights the need for doctors to be aware of CEP, as it can be mistaken for other conditions and reactions due to its rarity.
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