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The Study of Adolescent Resilience (SOAR): a research protocol.
Front Child Adolesc Psychiatry
March 2024
Military Population Health Directorate, Naval Health Research Center, San Diego, CA, United States.
Background: Adolescence is a particularly sensitive period of development for military-connected youth, given the socioemotional and physical changes that occur against the backdrop of the military career of their parent(s). Military-connected adolescents face unique stressors relative to their civilian counterparts, such as military relocations, parental absence due to deployments and trainings, and parental military-related physical and mental injury. These stressors may change family dynamics and disrupt social support networks, which can have lasting implications for adolescent health and well-being.
View Article and Find Full Text PDFRescuing ACE2-Deficiency-Mediated Nucleus Pulposus Senescence and Intervertebral Disc Degeneration by a Nanotopology-Enhanced RNAi System.
Adv Sci (Weinh)
January 2025
Department of Orthopedic Surgery, Changzheng Hospital, Naval Medical University, Shanghai, 200003, P. R. China.
Nucleus pulposus cell (NPC) senescence contributes to intervertebral disc degeneration (IVDD). However, the underlying molecular mechanisms are not fully understood. In this study, it is demonstrated that angiotensin-converting enzyme 2 (ACE2) counteracted the aging of NPCs and IVDD at the cellular and physiological levels.
View Article and Find Full Text PDFAn Inverse FEM for Structural Health Monitoring of a Containership: Sensor Network Optimization for Accurate Displacement, Strain, and Internal Force Reconstruction.
Sensors (Basel)
January 2025
Department of Mechanical Engineering, Politecnico di Milano, Via G. La Masa 1, 20156 Milano, Italy.
In naval engineering, particular attention has been given to containerships, as these structures are constantly exposed to potential damage during service hours and since they are essential for large-scale transportation. To assess the structural integrity of these ships and to ensure the safety of the crew and the cargo being transported, it is essential to adopt structural health monitoring (SHM) strategies that enable real-time evaluations of a ship's status. To achieve this, this paper introduces an advancement in the field of smart sensing and SHM that improves ship monitoring and diagnostic capabilities.
View Article and Find Full Text PDFLipid production from biofilms of Marinobacter atlanticus in a fixed bed bioreactor.
Microb Cell Fact
December 2024
Center for Biomolecular Science and Engineering, US Naval Research Laboratory, Washington, DC, 20375, USA.
Background: Biotechnologies that utilize microorganisms as production hosts for lipid synthesis will enable an efficient and sustainable solution to produce lipids, decreasing reliance on traditional routes for production (either petrochemical or plant-derived) and supporting a circular bioeconomy. To realize this goal, continuous biomanufacturing processes must be developed to maximize productivity and minimize costs compared to traditional batch fermentation processes.
Results: Here, we utilized biofilms of the marine bacterium, Marinobacter atlanticus, to produce wax esters from succinate (i.
Aberrant anatomy in the context of the critical view of safety.
Surg Endosc
December 2024
Department of Minimal Invasive and Bariatric, Surgery University Hospital of Indianapolis, Indianapolis, USA.
Background: The protective impact of the Critical View of Safety (CVS) approach on the vasculo-biliary injuries during laparoscopic cholecystectomy (LC) depends largely upon the understanding of the normal and variant anatomy. Structures exposed during the acquisition of the CVS can deviate from the typical dual configuration of the cystic duct and artery (gallbladder pedicle) representing either a third (supernumerary) or atypical in course (heterotopic) element. The aim of this study was to determine the identity and the frequency of these anatomical elements and to propose anatomic schemata that can guide the achievement of CVS by surgeons.
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