A study is presented of the cellular-humoral immunity in patients with typical meningococcemia complicated by infectious-toxic shock. Obtained data evidence significant changes of the cellular-humoral immunity in meningococcemias, especially those accompanied by infectious-toxic shock along with traditional methods the authors propose immunoregulatory and pathogenetic treatment: human immunoglobulin, aminocaproic acid, sodium, ethamsilate or dicinon, thymalin or T-activin, dopamin, rifampycin. The dosage of these drugs should be individual. The indications and efficiency should be controlled immunologically.

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