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Impact of COVID-19 on Respiratory Virus Infections in Children, Japan, 2018-2023.
Immun Inflamm Dis
March 2025
Pandemic Preparedness, Infection, and Advanced Research Center, The University of Tokyo, Tokyo, Japan.
Background: COVID-19, caused by SARS-CoV-2, was first documented in Japan in January 2020. We previously reported an increased risk of rhinovirus infections among children during the early phase of the COVID-19 pandemic. Here, we assessed the impact of COVID-19 on respiratory virus infections after SARS-CoV-2 spread nationwide.
View Article and Find Full Text PDFElderly Female with Cranial Polyneuropathy.
Indian J Otolaryngol Head Neck Surg
January 2025
Department of ENT, Government General Hospital, Karaikal, India.
Unlabelled: The recrudescence of Varicella Zoster Virus in the head and neck region often manifests as Ramsay Hunt Syndrome, characterised by facial nerve palsy, vesicular rash in the distribution of facial nerve and neuralgia. Rarely it causes cranial polyneuropathy (CP). We present a case of herpes zoster with CP, highlighting the diagnostic challenges and management in a resource-limited setting.
View Article and Find Full Text PDFDeucravacitinib, an oral, selective, allosteric tyrosine kinase 2 inhibitor, was effective and well tolerated at a dose of 6 mg once daily through 1 year (52 weeks) in patients with moderate to severe plaque psoriasis in the phase 3 POETYK PSO-1 and POETYK PSO-4 trials. Patients completing PSO-1 or PSO-4 could enter the ongoing POETYK long-term extension trial and receive open-label deucravacitinib. Safety and efficacy were evaluated through 3 years (148 weeks; data cutoff date: June 15, 2022) in Japanese patients in these trials.
View Article and Find Full Text PDFClinical characteristics of varicella-zoster virus central nervous system infection in 108 unimmunocompromised patients.
Front Neurol
February 2025
Department of Neurology, Affiliated Nanjing Brain Hospital, Nanjing Medical University, Nanjing, China.
Background: Varicella-zoster virus (VZV) central nervous system infection is typically observed in immunocompromised patients, and there is a lack of studies involving large samples of non-immunocompromised individuals. In this study, we retrospectively analyzed 108 non-immunocompromised patients diagnosed with VZV central nervous system infection.
Methods: This retrospective study was conducted in the Department of Neurology, Affiliated Nanjing Brain Hospital, Nanjing Medical University, China.
Vaccination and rheumatoid arthritis: an updated systematic review and meta-analysis of data from 25,949,597 participants.
BMC Public Health
March 2025
School of Basic Medical Sciences of Zhejiang, Chinese Medical University, Binwen Road, Binjiang District, Hangzhou, China.
Objectives: This systematic review and meta-analysis aimed to investigate the association between vaccinations and the risk of rheumatoid arthritis (RA), specifically addressing concerns about a potential increased risk among vaccinated individuals.
Methods: A systematic search for cohort studies and case-control studies examining the association between vaccinations and RA was conducted using Medical Subject Headings and relevant keywords across PubMed, EMBASE, and Cochrane Library databases from inception to September 2024. The risk of bias of included studies was assessed using the Newcastle-Ottawa Scale.
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