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Construction and preliminary trial test of a decision-making app for pre-hospital damage control resuscitation.
Chin J Traumatol
February 2025
State Key Laboratory of Trauma, Burn and Combined Injury, Department for Combat Casualty Care Training, Army Medical University, Chongqing, 400038, China.
Purpose: To construct a decision-making app for pre-hospital damage control resuscitation (PHDCR) for severely injured patients, and to make a preliminary trial test on the effectiveness and usability aspects of the constructed app.
Methods: Decision-making algorithms were first established by a thorough literature review, and were then used to be learned by computer with 3 kinds of text segmentation algorithms, i.e.
Transfusion of modified whole blood versus blood components therapy in patients with severe trauma: Randomized controlled trial protocol (WEBSTER trial).
Injury
January 2025
División de Cirugía de Trauma y Emergencias, Departamento de Cirugía, Fundación Valle del Lili, Cali, Colombia; Departamento de Cuidado Intensivo, Fundación Valle del Lili, Cali, Colombia; Departamento de Cirugía, Universidad del Valle, Cali, Colombia.
Hemostatic resuscitation is a mainstay in the management of trauma patients. Factors such as blood loss and tissue injury contribute to coagulation and hemodynamic status imbalances. Hemorrhage remains a leading cause of death in trauma patients, despite advances in strategies such as damage control surgery, massive transfusion protocol, and intensive care.
View Article and Find Full Text PDFNarrowing of the Racial Disparities Gap in Survival of Patients With Mycosis Fungoides: A Longitudinal Analysis of the SEER Database.
Clin Lymphoma Myeloma Leuk
February 2025
Ohio Health Blood and Marrow Transplant Program, Columbus, OH. Electronic address:
Background: Mycosis fungoides (MF) is the commonest subtype of cutaneous T-cell lymphoma. In the United States, prior studies reported that African Americans (AA) with MF had poor outcomes. Data characterizing differences in racial disparity outcomes over time are limited.
View Article and Find Full Text PDFPredicting Severe Radiation Pneumonitis in Patients With Locally-Advanced Non-Small-Cell Lung Cancer After Thoracic Radiotherapy: Development and Validation of a Nomogram Based on the Clinical, Hematological, and Dose-Volume Histogram Parameters.
Clin Lung Cancer
February 2025
Department of Radiation Oncology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, Shanghai, China. Electronic address:
Purpose: This study aimed to investigate the risk factors for severe radiation pneumonitis (RP) after thoracic radiotherapy (RT) in patients with locally advanced non-small cell lung cancer (NSCLC), develop a prediction model to identify high-risk groups, and investigate the impact of severe RP on overall survival (OS).
Methods: We retrospectively collected clinical, dosimetric, and hematological factors of patients with stage III NSCLC receiving thoracic RT without immunotherapy. The primary and secondary end points were severe RP and OS, respectively.
Hypovolemic and hemorrhagic shock are life-threatening conditions that, if untreated, rapidly lead to multi-organ failure and death. These conditions result from significant intravascular fluid or blood loss, causing critical organ hypoperfusion. The underlying pathophysiology involves complex hemodynamic, inflammatory, and coagulation disturbances that may progress to irreversible organ dysfunction.
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