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Prevalence and factors associated with potential clinically significant drug-drug interactions in patients with cardiovascular diseases at hospital admission.
Acta Pharm
December 2024
Department of Clinical Pharmacy, University Hospital Dubrava, 10000 Zagreb Croatia.
Cardiovascular diseases (CVDs) are the leading cause of mortality and morbidity globally. It is estimated that 17.9 million people died from CVDs in 2019, which represents 32 % of all deaths worldwide.
View Article and Find Full Text PDFEvaluation of Noise in Paediatric Dentistry and Change in Perception of Operators with Use of Ear Protection Devices.
Noise Health
January 2025
K M Shah Dental College and Hospital, Sumandeep Vidyapeeth deemed to be University, Waghodia, Vadodara - 391760, India.
Background: Noise sources in paediatric dental offices include machinery and children's cries and screams. Although the presence of occupational noise-induced hearing loss (ONIHL) among dental operators is established, preventive measures such as ear protection devices (EPDs) are not frequently employed as prophylactic intervention. The primary aim of this study was to quantitatively assess the noise levels in paediatric dental clinics and to qualitatively evaluate the operators' perception of noise with and without the use of EPDs.
View Article and Find Full Text PDFKinetic Oscillation Stimulation for the Preventive Treatment of Chronic Migraine: A Randomized, Double-Blind, Sham-Controlled Trial.
Neurology
February 2025
Department of Systems Neuroscience, University Medical Center Hamburg-Eppendorf, Germany.
Background And Objectives: The Chordate System administers kinetic oscillation stimulation (K.O.S) into the nasal cavity thereby potentially modulating the activity of trigemino-autonomic reflex.
View Article and Find Full Text PDFTrastuzumab-Pertuzumab Plus Eribulin or Taxane as First-Line Chemotherapy for Human Epidermal Growth Factor 2-Positive Locally Advanced/Metastatic Breast Cancer: The Randomized Noninferiority Phase III EMERALD Trial.
J Clin Oncol
January 2025
Department of Breast Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Purpose: Trastuzumab-pertuzumab (HP) plus taxane is a current standard first-line therapy for recurrent or metastatic human epidermal growth factor 2 (HER2)+ breast cancer (BC). We investigated noninferiority of eribulin to a taxane when combined with dual HER2 blockade as first-line systemic treatment for locally advanced/metastatic HER2+ BC.
Methods: In the phase III EMERALD trial (target sample size, 480; ClinicalTrials.
Hepatic Arterial Infusion Pump Complication With Multimodal Radiologic and Anatomic Review.
Clin Nucl Med
December 2024
From the Department of Radiology, UT Southwestern Medical Center, Dallas, TX.
Hepatic arterial infusion therapy involves surgically implanting a subcutaneous hepatic arterial infusion pump with the catheter tip at the hepatic artery. This pump directly delivers chemotherapy to the liver, which may reduce systemic toxicity, improve resectability, and treat unresectable hepatic lesions. This therapy is used in primary or metastatic hepatic malignancies.
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