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Study of thulium-167 cyclotron production: a potential medically-relevant radionuclide.
Front Chem
October 2023
Center for Radiopharmaceutical Sciences (CRS), Paul Scherrer Institute, Villigen-PSI, Switzerland.
Targeted Radionuclide Therapy is used for the treatment of tumors in nuclear medicine, while sparing healthy tissues. Its application to cancer treatment is expanding. In particular, Auger-electron emitters potentially exhibit high efficacy in treating either small metastases or single tumor cells due to their short range in tissue.
View Article and Find Full Text PDFProduction cross sections of samarium-153 and -145 via alpha-particle-induced reactions on natural neodymium.
Appl Radiat Isot
September 2022
Institute for Nuclear Research, ATOMKI, 4026, Debrecen, Hungary.
Production cross sections of Sm via alpha-particle-induced reactions on Nd were measured up to 23 MeV. The stacked-foil activation technique and high-resolution gamma-ray spectrometry were adopted for the measurement. The obtained cross sections were compared with the literature data and the TENDL-2019 and TENDL-2021 values.
View Article and Find Full Text PDFCyclotron production and radiochemical purification of terbium-155 for SPECT imaging.
EJNMMI Radiopharm Chem
November 2021
Center for Radiopharmaceutical Sciences, ETH-PSI-USZ, Paul Scherrer Institute, 5232, Villigen-PSI, Switzerland.
Background: Terbium-155 [T = 5.32 d, Eγ = 87 keV (32%) 105 keV (25%)] is an interesting radionuclide suitable for single photon emission computed tomography (SPECT) imaging with potential application in the diagnosis of oncological disease. It shows similar decay characteristics to the clinically established indium-111 and would be a useful substitute for the diagnosis and prospective dosimetry with biomolecules that are afterwards labeled with therapeutic radiolanthanides and pseudo-radiolanthanides, such as lutetium-177 and yttrium-90.
View Article and Find Full Text PDFMolecular evolution and genomic characteristics of genotype H1 of measles virus.
J Med Virol
February 2022
National Health Commission (NHC) Key Laboratory of Medical Virology and Viral Diseases. National Institute for Viral Disease Control and Prevention, China CDC;, WHO WPRO Regional Reference Measles/Rubella Laboratory, Beijing, China.
Measles is one of the most infectious diseases of humans. It is caused by the measles virus (MeV) and can lead to serious illness, lifelong complications, and even death. Whole-genome sequencing (WGS) is now available to study molecular epidemiology and identify MeV transmission pathways.
View Article and Find Full Text PDFMeasurements of (186)Re production cross section induced by deuterons on (nat)W target at ARRONAX facility.
Nucl Med Biol
May 2014
1 Laboratoire SUBATECH, CNRS/IN2P3-EMN-Université, 4 rue Alfred Kastler, 44307 Nantes, France.
Introduction: The ARRONAX cyclotron, acronym for "Accelerator for Research in Radiochemistry and Oncology at Nantes Atlantique" is a new facility installed in Nantes, France. A dedicated program has been launched on production of innovative radioisotopes for PET imaging and for β- and α targeted radiotherapy using protons or α particles. Since the accelerator is also able to deliver deuteron beams up to 35 MeV, we have reconsidered the possibility of using them to produce medical isotopes.
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