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The 2022 revision of the World Health Organization classification of tumors of the urinary system and male genital organs: advances and challenges.

Hum Pathol

June 2023

Department of Pathology and Laboratory Medicine, Warren Alpert Medical School of Brown University, Lifespan Academic Medical Center, Providence, RI, 02903, USA. Electronic address:

The fifth edition of the World Health Organization (WHO) classification of urinary and male genital organ tumors has been recently published in 2022. The application of molecular profiling has made a substantial impact on the classification of urologic tumors. The new WHO classification introduces a group of molecularly well-defined renal tumor subtypes.

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Promyelocytic leukemia zinc finger is a zinc finger transcription factor that functions as a transcriptional repressor. Its expression has been shown to be down-regulated in hematopoietic, melanocytic, and mesothelial malignancies. Histone H1.

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Radiopeptide imaging and therapy in the United States.

J Nucl Med

December 2011

Department of Radiology, Carver College of Medicine, University of Iowa, Iowa City, Iowa 52242, USA.

Radiolabeled peptides targeted against receptors on the cell surface have been shown to be remarkably specific and effective in the diagnosis and therapy of malignant disease. Much of the early work in this field took place outside the United States, but in recent years the research effort within the United States has accelerated. Most of the initial studies in the United States focused on somatostatin receptor ligands.

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[Eruptive naevi associated with octreotide treatment].

Ann Dermatol Venereol

October 2011

Cabinet de dermatologie, Saint-Étienne, France.

Background: Octreotide is a synthetic octapeptide having properties related to those of natural somatostatin, a hypothalamic hormone. We report a case of eruptive naevus in patients treated with octreotide.

Patients And Methods: A 52-year-old man consulted for multiple achromic naevi of recent onset.

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A 71-year-old man presented to the authors' clinic for evaluation of a red line under his right thumb. He noticed a red streak develop during the past year. It slowly grew in width and become more prominent in color (Figure 1).

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