A prospective cohort study of a twice weekly exercise programme for six months was undertaken to determine the benefits of an exercise class for 28 elderly women following hip surgery. The effects of the exercise programme were monitored using cycle ergometry. Walking speed was measured on entry and at 3, 6 and 12 months. Twenty-six subjects completed the programme with an overall attendance rate of 88%. Measures of fitness, calculated from cycle ergometry, did not improve significantly apart from test duration. In contrast there was a significant improvement in mean walking speed, with a 50% increase between 0 and 3 months and a further 21% increase between 3 and 6 months. This improvement was maintained at 12 months.
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Digit Health
January 2025
School of Public Management, East China Normal University, Shanghai, China.
Objectives: This study aims to investigate whether social networks and physical exercise mediate the relationship between new and constant use of intelligent virtual assistants (IVAs) and cognitive function in older adults in China and explore the potential differences across living arrangements and education levels.
Methods: This study utilized nationally representative longitudinal data from 2018 to 2020, including a sample of 8343 older adults aged 60-80. A path-analytic model was employed to examine the relationship between IVAs use and cognitive function, as well as the mediating roles of social networks and physical exercise.
Neural Regen Res
January 2025
Department of Rehabilitation Medicine, The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, Guangdong Province, China.
Alzheimer's disease is the primary cause of dementia and imposes a significant socioeconomic burden globally. Physical exercise, as an effective strategy for improving general health, has been largely reported for its effectiveness in slowing neurodegeneration and increasing brain functional plasticity, particularly in aging brains. However, the underlying mechanisms of exercise in cognitive aging remain largely unclear.
View Article and Find Full Text PDFEur Respir J
January 2025
Université Paris-Saclay, INSERM Unité Mixte de Recherche en Santé 999 (HPPIT), Service de Pneumologie et Soins Intensifs Respiratoires, Hôpital Bicêtre (Assistance Publique-Hôpitaux de Paris), Le Kremlin-Bicêtre, France.
Introduction: Pulmonary arterial hypertension (PAH) is a progressive disease associated with significant morbidity and mortality. Sotatercept is a first-in-class activin signalling inhibitor that acts to restore the balance between the growth-promoting and growth-inhibiting signalling pathways.
Methods: This post-hoc, exploratory, pooled analysis combines data from the double-blind placebo periods of the phase 2 PULSAR (NCT03496207) and phase 3 STELLAR (NCT04576988) studies.
Respir Med
January 2025
Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada; Division of Respirology, Temerty Faculty of Medicine, University Health Network, University of Toronto, Toronto, ON, Canada. Electronic address:
Background/objectives: Pulmonary rehabilitation (PR) benefits individuals with chronic respiratory conditions beyond COPD; however, the quality of online resources has not been evaluated. The aims of this study were to assess the content, quality, and comprehensibility of YouTube videos that provide PR to individuals with chronic lung diseases other than COPD.
Methods: A search was conducted on YouTube for videos related to PR on non-COPD conditions, with the first 350 videos screened for eligibility (2004-2024).
Life Sci
January 2025
Laboratory Mobility, Aging & Exercise-ER20296 (MOVE), University of Poitiers, Faculty of Sport Sciences, STAPS, Poitiers, France.
Aging is a multifaceted biological process characterized by a progressive decline in physiological functions and heightened vulnerability to diseases, shaped by genetic, environmental, and lifestyle factors. Among these, cold exposure has garnered interest for its potential anti-aging benefits. This review examines the impact of cold exposure on aging, focusing on key physiological processes such as inflammation, oxidative stress, metabolic regulation, and cardiovascular health.
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