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Deep eutectic solvents in analysis, delivery and chemistry of pharmaceuticals.
Int J Pharm
January 2025
Department of Analytical Chemistry, Applied Chemometrics and Molecular Modelling, Vrije Universiteit Brussels (VUB), Laarbeeklaan 103, Brussels 1090 Belgium. Electronic address:
Deep eutectic solvents (DES) have an emerging scientific role, assisting modern pharmaceutics. They are uniquely supporting the resolution of crucial issues, such as the effective extraction and isolation of bio-actives. They act as media and catalysts for pharmaceutical drug synthesis, and as green solvents and modifiers in pharmaceutical analysis.
View Article and Find Full Text PDFDigital Information Exchange Between the Public and Researchers in Health Studies: Scoping Review.
J Med Internet Res
January 2025
Department of Prevention and Evaluation, Leibniz Institute for Prevention Research and Epidemiology - BIPS, Bremen, Germany.
Background: Information exchange regarding the scope and content of health studies is becoming increasingly important. Digital methods, including study websites, can facilitate such an exchange.
Objective: This scoping review aimed to describe how digital information exchange occurs between the public and researchers in health studies.
Aging women in Russia: Between sexless and sexy oldies.
J Women Aging
January 2025
Department of Sociology, European University at St. Petersburg, St Petersburg, Russia.
Women's sexuality as a dimension of embodied identity is shaped and constrained by social norms of gender and age and negotiated by women in complex ways. Discourses of hegemonic bodily normativity ascribe a sexless subjectivity to Russian women in their post-reproductive years, contributing to their social exclusion. At the same time, in modern Russian society a neoliberal concept of "successful active aging" is gradually changing understandings of aging, making later-life sexuality more visible and legitimate.
View Article and Find Full Text PDFEnhancing cognitive accessibility in assessments for children with neurodisability: development and implementation of an adaptation tracking questionnaire.
Disabil Rehabil
January 2025
Murdoch Children's Research Institute, The University of Melbourne, Melbourne, Australia.
Purpose: The range of impairments in children with neurodisability (ND) complicates data collection, yet individualising materials and procedures could enable more children to self-report. This study introduces the Cognitive Accessibility Tracking Questionnaire (CATQ), designed to monitor changes enhancing accessibility ("adaptations") in interview-administered patient-reported outcome measures (PROMs). The CATQ is used in a longitudinal study of mental health and participation in children with ND investigating adaptation use and its utility in assessing the risk of bias introduced by these adaptations.
View Article and Find Full Text PDFThe sociolinguistic foundations of language modeling.
Front Artif Intell
January 2025
Department of Linguistics and Communication, University of Birmingham, Birmingham, United Kingdom.
In this article, we introduce a sociolinguistic perspective on language modeling. We claim that language models in general are inherently modeling , and we consider how this insight can inform the development and deployment of language models. We begin by presenting a technical definition of the concept of a variety of language as developed in sociolinguistics.
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