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http://dx.doi.org/10.1530/acta.0.0050249DOI Listing

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The thyroliberin (TRH) test was used for examining 343 persons. The substance was injected intravenously in a dose of 200 micrograms, with thyrotropin (TTH) being studied by radioimmunoassay before and 30 minutes after stimulation. The test was performed over time after operation and drug treatment of diffuse toxic goiter in the course of 1-3 years of follow up.

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Altogether 136 patients with thyrotoxicosis complicated by atrial fibrillation were treated. After drug treatment alone and strumectomy if indicated, over two-thirds of the patients showed sinus rhythm recovery after the attainment of euthyrosis even before institution of the treatment with antiarrhythmic drugs. It is concluded that in patients with removed thyrotoxicosis, uneliminated atrial fibrillation does not interfere with surgery which should not be postponed, since 10% of the patients demonstrate unaided sinus rhythm recovery in the immediate postoperative period.

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