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Microbial community analysis of supragingival plaque in patients with fixed prostheses.

J Prosthet Dent

January 2025

Associate Professor, Department of Stomatology, The Fifth Affiliated Hospital of Sun Yat-sen University, Xiangzhou, Zhuhai City, Guangdong, PR China. Electronic address:

Statement Of Problem: Harmony between prostheses and periodontal tissues is essential. The presence of a fixed prosthesis has been reported to increase the risk of periodontal lesion onset in abutment teeth and to affect longevity. However, studies comparing the supragingival plaque biofilm on fixed prostheses and natural teeth are lacking.

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[Impact of tumor lysis syndrome on the prognosis of pediatric mature B-cell lymphoma].

Zhonghua Xue Ye Xue Za Zhi

December 2024

Department of Pediatric Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.

This study aimed to investigate the effect of tumor lysis syndrome (TLS) on the prognosis of children and adolescents with intermediate- or high-risk high-grade mature B-cell nonHodgkin lymphoma (HG B-NHL) . This study collected the clinical data and prognosis of 283 patients aged <18 years with newly diagnosed intermediate- or high-risk HG B-NHL treated at the Sun Yat-sen University Cancer Center from January 2010 to December 2022. The clinical characteristics, laboratory indicators during TLS, and prognosis of the patients were analyzed.

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Neuronal cell type specific roles for Nprl2 in neurodevelopmental disorder-relevant behaviors.

Neurobiol Dis

January 2025

The University of Texas Southwestern Medical Center, Department of Neurology, Dallas, TX, United States of America; The University of Texas Southwestern Medical Center, Department of Psychiatry, Dallas, TX, United States of America; The University of Texas Southwestern Medical Center, Department of Pediatrics, Dallas, TX, United States of America; The University of Texas Southwestern Medical Center, Department of Neuroscience, Dallas, TX, United States of America. Electronic address:

Loss of function in the subunits of the GTPase-activating protein (GAP) activity toward Rags-1 (GATOR1) complex, an amino-acid sensitive negative regulator of the mechanistic target of rapamycin complex 1 (mTORC1), is implicated in both genetic familial epilepsies and NDDs (Baldassari et al., 2018). Previous studies have found seizure phenotypes and increased activity resulting from conditional deletion of GATOR1 function from forebrain excitatory neurons (Yuskaitis et al.

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This review follows the PRISMA guidelines to provide a systematic review of 115 peer reviewed articles that used non-targeted analysis (NTA) methods to detect per- and polyfluoroalkylated substances (PFAS). This literature highlights the significant positive impact of NTA in understanding PFAS in the environment. Within the literature a geographical bias exists, with most NTA studies (∼60 %) conducted in the United States and China.

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Integrated transcriptomic and lipidomic analysis reveals that arachidonic acid mediates the allograft-induced stress response in Pinctada fucata martensii.

Comp Biochem Physiol Part D Genomics Proteomics

December 2024

Fisheries College, Guangdong Ocean University, Zhanjiang 524088, China; Guangdong Science and Innovation Center for Pearl Culture, Zhanjiang 524088, China; Pearl Breeding and Processing Engineering Technology Research Center of Guangdong Province, Zhanjiang 524088, China; Guangdong Provincial Key Laboratory of Aquatic Animal Disease Control and Healthy culture, Zhanjiang 524088, China. Electronic address:

This study investigated the protective effect of arachidonic acid (ARA) against the allograft-induced stress response in Pinctada fucata martensii by characterizing pearl production traits and changes in genes and lipids during postoperative care. Survival and pearl production traits were higher in the ARA treatment group (ARAG) than in the control group (CG). There were 1536 differentially expressed genes (DEGs) in CG-1d vs ARAG-1d and 833 DEGs in CG-3d vs ARAG-3d.

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