The distribution of blood groups of the ABO system is different in the rhesus-positive and rhesus-negative subpopulations. An increasing frequency of the phenotype A2 in the rhesus-negative subpopulation is observed. The calculation of the gene frequency reveals a deficiency of genes A1 and O, and the increasing frequency of genes A2 and B in the rhesus-negative part of the population. On the whole for the inhabitants of Minsk the ratio of the phenotypes A2/A1 differs significantly from the corresponding index for the republic as a whole, which is the evidence of a significant migration of the population in the capital of Byelorussia. The observed correlative dependences in the distribution of the genes of ABO system and of the rhesus system permit to recommend the accomplishment of a scientific search between the hereditary pathology and the susceptibility to different diseases and blood groups taking into consideration the rhesus appurtenance of the populations studied.

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