[Lipoperoxides and atherosclerosis].

Cas Lek Cesk

Výzkumná angiologická laborator pri IV, interní klinice 1. lékarské fakulty Univerzity Karlovy, Praha.

Published: November 1992

AI Article Synopsis

  • The theory connects lipoperoxides to atherosclerosis and thrombosis, integrating free oxygen radicals, vascular wall damage, and lipid metabolism issues.
  • It offers a fresh perspective on established risk factors associated with these conditions.
  • The theory is strengthened by recent advances in molecular biology, particularly regarding monocytes and macrophages.

Article Abstract

The theory of the pathogenetic role of lipoperoxides in atherosclerosis and thrombosis is very topical at present. It unifies the theory on the role of free oxygen radicals with the theory of damage of the vascular wall and with the theory of impaired lipid metabolism. It makes possible also a new interpretation of known risk factors. It is also based on the most recent results of molecular biology (role of monocytes-macrophages).

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