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Retrospective Cohort Study of Elderly Users of Single- or Multiple-Inhaler Triple Therapy for the Treatment of Asthma in the USA.
Pulm Ther
January 2025
US Medical Affairs, GSK, ATC Fowler Building, 410 Blackwell Street, Durham, NC, 27701, USA.
Introduction: Escalation to single- or multiple-inhaler triple therapy (SITT; MITT) is a recommended option for patients with asthma who remain uncontrolled by medium-dose inhaled corticosteroid/long-acting β-agonist; however, characterization of elderly users of triple therapy is limited. This real-world cohort study describes demographics and clinical characteristics of elderly patients with asthma with and without comorbid chronic obstructive pulmonary disease (COPD) who are new users of triple therapy, and asthma treatment patterns preceding triple therapy initiation.
Methods: This retrospective cohort study used administrative claims data from the Optum Clinformatics Data Mart database.
Claim Suppression of Occupational Injuries and Illnesses Among Precariously Employed Immigrant Workers in Ontario.
New Solut
January 2025
South Asian Women and Immigrants' Services, Toronto, Ontario, Canada.
Employers sometimes hinder the appropriate reporting of claims to workers' compensation, a phenomenon termed claim suppression. While the magnitude of claim suppression is difficult to quantify, various reports have identified it as a significant concern. In response, several Canadian jurisdictions, such as Ontario in 2015, introduced legislation addressing claim suppression.
View Article and Find Full Text PDFAnti-Tumor Effects of Venom on Liver Cancer: In Vitro and In Vivo Studies.
Toxins (Basel)
December 2024
School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Despite the popular belief in the anti-tumor properties of venom (VBV), there is limited scientific evidence to support this claim. This study is the first to examine the anti-tumor effects of VBV on liver cancer, both alone and in combination with cisplatin (DDP), through in vitro and in vivo experiments. In vitro experiments evaluated VBV and its combination with DDP on HepG2 cell proliferation, invasion, migration, and apoptosis.
View Article and Find Full Text PDFOccupational therapy treatment of public safety personnel with work-related psychological injuries: analyzing Ontario worker's compensation data from 2017-2021.
Front Psychiatry
January 2025
School of Rehabilitation Therapy, Queen's University, Kingston, ON, Canada.
This study explored the usage of occupational therapy treatment with psychologically injured public safety personnel (PSP) from Ontario, Canada. We used a descriptive quantitative approach with summary data provided by the Workplace Safety and Insurance Board (WSIB) of Ontario documenting occupation therapy (OT) treatment of psychologically injured PSP who had an approved WSIB Mental Stress Injury Program (MSIP) claim between 2017 and 2021. Variables examined included demographics, career type, injury type, and return to work (RTW) outcomes.
View Article and Find Full Text PDFThe Rapid Rise of Silicosis in Victoria, Australia Associated With Artificial Stone Countertop Industry Work.
Am J Ind Med
January 2025
Monash Centre for Occupational and Environmental Health, School of Public Health & Preventive Medicine, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Victoria, Australia.
Background: The fabrication and installation of artificial (engineered) stone countertops is a relatively new cause of silicosis. Our aim was to investigate silicosis rates in Victoria, Australia, and the association with stone countertop industry work.
Methods: Workers' compensation claims for silicosis from January 1, 1991 to December 31, 2022 were analyzed across 8-year time periods.
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