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Similar Publications
A retrospective analysis of Stewart-Treves syndrome in the context of chronic lymphedema.
An Bras Dermatol
May 2023
Department of Lymphatic Surgery, Beijing Shijitan Hospital, Capital Medical University, Beijing, China. Electronic address:
Article Synopsis
- Stewart-Treves syndrome (STS) is a type of angiosarcoma that can develop in individuals with chronic lymphedema, and this article analyzes characteristics of 22 patients diagnosed with STS over an 11-year period.
- Key findings show that patients typically presented with skin nodules, red rashes, and various symptoms like pain and lymphadenopathy, with imaging tests revealing varying degrees of effectiveness in diagnosis.
- The study concludes that early intervention in lymphedema and vigilant monitoring for malignant signs are crucial to improve STS diagnosis and treatment outcomes, although further clinical trials are necessary to deepen understanding of STS development.
Remarkable response to radiation therapy with concurrent chemotherapy in Stewart-Treves syndrome.
J Cancer Res Ther
August 2022
Department of Radiology, The University of Tokyo Hospital, Tokyo, Japan.
Article Synopsis
- - Stewart-Treves syndrome (STS) is a rare form of skin cancer (cutaneous angiosarcoma) that develops in patients with long-term lymphedema, leading to a very poor prognosis if untreated (median survival: 5-8 months).
- - An 82-year-old woman with STS underwent a treatment regimen of concurrent chemoradiotherapy, which included radiation therapy and chemotherapy with docetaxel and interleukin-2.
- - After treatment, she experienced some acute side effects but showed significant improvement, with imaging tests indicating that the cancer lesions had disappeared and no recurrence occurred over the following 4 years.
Stewart-Treves syndrome and other cutaneous malignancies in the context of chronic lymphedema: a systematic review.
Int J Dermatol
January 2022
Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Article Synopsis
- Angiosarcoma, known as Stewart-Treves syndrome (STS), is a rare but deadly cancer that can develop in tissues affected by long-term lymphedema, and this review compiles data on its traits and outcomes alongside other skin cancers related to lymphedema.
- A total of 369 patients were analyzed, with 89.7% having STS, mostly affecting middle-aged women and associated with prior cancer and radiation history; STS typically appears 14.9 years after lymphedema onset, with a significant mortality rate.
- Treatment choice significantly impacts survival, with surgical excision leading to better outcomes than radiotherapy, highlighting the need for more research on the underlying causes and management strategies
Stewart-Treves syndrome associated with disuse edema in amyotrophic lateral sclerosis.
J Dermatol
September 2021
Department of Dermatology, St. Marianna University School of Medicine, Kawasaki, Japan.
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