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Management of Acute Pulmonary Embolism: A Review.
J Assoc Physicians India
November 2024
Consultant and Head, Department of Cardiology, Safdarjung Hospital, Delhi, India.
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- Pulmonary embolism (PE) is a significant health concern in India, often missed or poorly managed, leading to increased risk of cardiovascular issues in hospitalized patients.
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The third-generation anticoagulants: factors XI, XII, and XIII inhibitors.
Egypt Heart J
October 2024
Department of Cardiology, King George's Medical University, Shahmina Road, Chowk, Lucknow, Uttar Pradesh, 226003, India.
Article Synopsis
- * Factor XI inhibitors have shown better efficacy and safety compared to enoxaparin in reducing venous thromboembolic incidents, while factor XII inhibitors could also lower bleeding risks based on preliminary animal research.
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The efficacy and safety of direct oral anticoagulants in the treatment of the acute phase of heparin-induced thrombocytopenia: A systematic review.
Am J Health Syst Pharm
September 2024
The University of Toledo College of Pharmacy and Pharmaceutical Sciences, Toledo, OH, USA.
Purpose: To investigate the safety and efficacy of direct oral anticoagulants (DOACs) in the treatment of the acute phase of heparin-induced thrombocytopenia (HIT).
Summary: A systematic review of the literature was conducted on PubMed, MEDLINE, Embase, and Web of Science Core Collection through July 2023. Search terms included "heparin-induced thrombocytopenia AND direct-oral-anticoagulants" in addition to a list of oral anticoagulants.
Unlocking the potential of fondaparinux: guideline for optimal usage and clinical suggestions (2023).
Front Pharmacol
March 2024
Department of Pharmacy, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
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- Thromboembolic disease poses significant health risks, leading to high rates of disability and financial burdens on society, with anticoagulant medications being the main treatment.
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Polyester urethane urea (PEUU) functionalization for enhanced anti-thrombotic performance: advancing regenerative cardiovascular devices through innovative surface modifications.
Front Bioeng Biotechnol
September 2023
Department of Biomedical Engineering, Universidad de los Andes, Bogotá, Colombia.
Thrombogenesis, a major cause of implantable cardiovascular device failure, can be addressed through the use of biodegradable polymers modified with anticoagulating moieties. This study introduces a novel polyester urethane urea (PEUU) functionalized with various anti-platelet deposition molecules for enhanced antiplatelet performance in regenerative cardiovascular devices. PEUU, synthesized from poly-caprolactone, 1,4-diisocyanatobutane, and putrescine, was chemically oxidized to introduce carboxyl groups, creating PEUU-COOH.
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