Endometrial, endocervical, and urethral specimens were obtained from 16 nonpregnant women with a history of habitual abortions. Chlamydia were isolated from the endometria of 4 women, but only in one case chlamydial intracytoplasmic incorporations in endometrial cells were detectable by the Romanovsky Giemza staining. Endometrial Chlamydia infection was diagnosed in 5 of the 16 patients. No Chlamydia were isolated from the cervix uteri or urethra of 2 patients with endometrial involvement. The study has demonstrated that eradication of intrauterine chlamydial infection before pregnancy improves the efficacy of treatment of habitual abortions. It is possible that asymptomatic chlamydial endometrial infection is injurious for the placenta.

Download full-text PDF

Source

Publication Analysis

Top Keywords

chlamydia infection
8
habitual abortions
8
chlamydia isolated
8
endometrial
5
[endometrial chlamydia
4
infection
4
infection women
4
women habitual
4
habitual abortion]
4
abortion] endometrial
4

Similar Publications

Surveillance for variants escaping detection with the Aptima Combo 2 assay in Canada from 2019 to 2021.

Microbiol Spectr

January 2025

National Microbiology Laboratory Branch, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.

Unlabelled: Nucleic acid amplification tests (NAATs) are the method of choice for diagnosis, but these strategies are susceptible to target site mutations. variants escaping detection with the Aptima Combo 2 (AC2) assay on the Hologic Panther instrument from 23S rRNA mutations have been reported in Nordic countries, England, Japan, and the United States. Given the potential for false negative results, this study investigated whether strains of with AC2 target site mutations were present in Canada.

View Article and Find Full Text PDF

Antibodies directed against bacterial antigens in sera of Polish patients with primary biliary cholangitis.

Front Cell Infect Microbiol

January 2025

Clinic of Polish Gastroenterology Foundation, Warsaw, Poland.

Background: Primary biliary cholangitis (PBC) is a cholestatic, autoimmune liver disease with the presence of characteristic autoantibodies. The aim of the work was to determine the level of antibodies directed against bacterial antigens: (anti-anti), (anti-), (anti- ) and () in sera of PBC patients. We also performed studies on the impact of the bacterial peptides on the specific antigen-antibody binding.

View Article and Find Full Text PDF

Background: To explore the effect of non-pharmacological interventions (NPIs) on respiratory pathogen profiles among hospitalized infants aged 0-3 months in Beijing during the coronavirus disease 2019 (COVID-19) pandemic.

Methods: Respiratory specimens were collected from 1,184 infants aged 0-3 months who were hospitalized for acute respiratory infection at the Children's Hospital affiliated with the Capital Institute of Pediatrics from January 2018 to December 2023. The data were divided into three groups-the pre-epidemic (January 2018 to December 2019), epidemic prevention and control (January 2020 to December 2022), and post-epidemic (January 2023 to December 2023) groups-based on the outbreak of COVID-19 and the implementation and termination of NPIs.

View Article and Find Full Text PDF

Alzheimer's Disease (AD) is the most prevalent type of dementia and is characterized by the presence of senile plaques and neurofibrillary tangles. There are various theories concerning the causes of AD, but the connection between viral and bacterial infections and their potential role in the pathogenesis of AD has become a fascinating area of research for the field. Various viruses such as (HSV-1), (EBV), Cytomegalovirus (CMV), influenza viruses, and Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), as well as bacteria such as (CP), (HP), (), Spirochetes and eukaryotic unicellular parasites (e.

View Article and Find Full Text PDF

Glycosaminoglycans (GAGs) play a pivotal role in pathogen attachment and entry into host cells, where the interaction with GAGs is critical for a diverse range of bacteria and viruses. This study focuses on elucidating the specific interactions between sulfated GAGs and the adhesin OmcB (Outer membrane complex protein B) of Chlamydia species, examining how structural characteristics of GAGs, such as sulfation degree and molecular weight, influence their binding affinity and thereby affect bacterial infectivity. A surface-based binding assay is established to determine the binding constants of OmcB with various GAGs.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!