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Female Brain and Endocrinological Research-Veteran (FemBER-Vet) study: A study protocol for identifying endocrinological, lifestyle and psychosocial determinants of brain health outcomes in female veterans for future intervention success.
PLoS One
January 2025
Female Brain & Endocrine Health Research (FemBER) Consortium.
Background: Recent studies have demonstrated a greater risk of dementia in female veterans compared to civilians; with the highest prevalence noted for former service women with a diagnosis of psychiatric (trauma, alcoholism, depression), and/or a physical health condition (brain injury, insomnia, diabetes). Such findings highlight the need for increased and early screening of medical and psychiatric conditions, and indeed dementia, in the female veteran population. Further, they call for a better understanding of the underlying biopsychosocial mechanisms that might confer heightened risk for female veterans, to tailor preventative and interventional strategies that support brain health across the lifespan.
View Article and Find Full Text PDFHistological Features and Gene Expression Profiling in Lung Transplantation From Donation After Circulatory Death.
Arch Bronconeumol
January 2025
Department of Thoracic Surgery and Lung Transplantation, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain; Surgery Department, Medical School, Universidad Autónoma de Madrid (UAM), IDIPHISA, Madrid, Spain.
Reproductive Physiology and Molecular Mechanisms Underlying Testicular Development and Spermatogenesis in Echinoderms: A Marine Invertebrate Deuterostomes.
Mol Reprod Dev
January 2025
The Key Laboratory of Mariculture, Ministry of Education, College of Fisheries, Ocean University of China, Qingdao, China.
Echinoderms exhibit a wide range of reproductive strategies as adaptations to variable environments. The processes of gonadal development, germ cell differentiation, and spermatogenesis in echinoderms are crucial physiological processes that warrant further in-depth exploration. This review systematically summarizes research from early basic sciences to recent studies on male gonadal development and spermatogenesis, encompassing morphology, histology, physiology, cell biology, developmental biology, and evolutionary biology.
View Article and Find Full Text PDFPlasma S100A8/A9 level predicts response to immune checkpoint inhibitors in patients with advanced non-small cell lung cancer.
Sci Rep
January 2025
Department of Allergy and Respiratory Medicine, Okayama University Hospital, 2-5-1 Shikata-cho, Kita-ku, Okayama, Japan.
Blood-based predictive markers for the efficacy of immune checkpoint inhibitors (ICIs) have not yet been established. We investigated the association of the plasma level of S100A8/A9 with the efficacy of immunotherapy. We evaluated patients with unresectable stage III/IV or recurrent non-small cell lung cancer (NSCLC) who were treated with ICIs at Okayama University Hospital.
View Article and Find Full Text PDFRecommendations on the management of meningioma and sex hormone therapy: The results of a collaborative effort between neurosurgical, endocrine and gynecological societies.
Brain Spine
December 2024
Department of Gynecology, CHU de Liege, Liège, Belgium.
Introduction: Exogenous and endogenous sex hormones, especially Progesterone agonists, may be causally linked to meningioma progression. Cessation of treatment leads to stabilization or regression of Progestin-induced meningioma. In many cases, avoiding sex hormone therapy may be possible in the context of meningioma treatment.
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