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Left Coronary Artery-Right Ventricle Fistula Case Report: Optimal Treatment Decision.
Medicina (Kaunas)
January 2025
Cardiovascular Institute "Dedinje", 111040 Belgrade, Serbia.
Coronary artery fistulas (CAFs) are rare congenital anomalies, presenting in 0.05-0.9% of cases, characterized by an aberrant connection between a coronary artery and a cardiac chamber or great vessel.
View Article and Find Full Text PDFBackground/objectives: The failure of physiological left-right (LR) patterning, a critical embryological process responsible for establishing the asymmetric positioning of internal organs, leads to a spectrum of congenital abnormalities characterized by laterality defects, collectively known as "heterotaxy". biallelic variants have recently been associated with heterotaxy syndrome and congenital heart defects (CHD). However, the genotype-phenotype correlations and the underlying pathogenic mechanisms remain poorly understood.
View Article and Find Full Text PDFAdvanced Imaging for Congenital Left Ventricular Diverticulum in a Dog: The Role of Electrocardiosynchronous CT.
Animals (Basel)
January 2025
Veterinary Teaching Hospital, Tokyo University of Agriculture and Technology, Tokyo 183-8538, Japan.
A 2-month-old Shiba Inu was presented to an emergency veterinary clinic with decreased activity and was diagnosed with pulmonary hypertension secondary to a ventricular septal defect. The dog was referred to the TUAT Veterinary Medical Center for further evaluation. During treatment, a diverticulum was incidentally identified at the apex of the left ventricle.
View Article and Find Full Text PDFHydrolethalus Syndrome: A Case of a Rare Congenital Disorder.
Diagnostics (Basel)
January 2025
Department of Dentistry, Faculty of Dentistry, "Vasile Goldiș" Western University of Arad, 94-96 Revolutiei Blvd., 310025 Arad, Romania.
This is a fatal case of multiple complicated congenital anomalies displaying several symptoms consistent with hydrolethalus syndrome. The newborn's phenotype is characterized by a combination of serious anatomical abnormalities such as open-book cerebral hemispheres, defective lobulation of the lungs (one lobe on the left, two on the right), a smaller right kidney, a smooth cerebral surface, and a specific keyhole-shaped defect in the skull base, primarily associated with hydrocephalus.
View Article and Find Full Text PDFPatent foramen ovale: a variant of normal or a true congenital heart disease?
Cardiovasc Pathol
January 2025
Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua Medical School, Padova, Italy. Electronic address:
Foramen ovale plays a key role in foetal circulation, however it may remain patent after birth throughout the life. Its patency is so frequent in healthy people (27-35%), such as to be considered a variant of normal. It is at risk of complications, like paradoxical embolism by right to left shunt with stroke, migraine, temporary blindness, as well as aneurysm, thrombosis and endocarditis of the fossa ovalis.
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