We report on the distribution spectra of the fluctations in the amount of power injected into a liquid crystal undergoing electroconvective flow. The probability distribution functions (PDFs) of the fluc-tuations as well as the magnitude of the fluctuations have been determined in a wide range of imposed stress both for unconfined and confined flow geometries. These spectra are compared to those found in other systems held far from equilibrium, and find that in certain conditions we obtain the universal PDF form reported by Phys. Rev. Lett. 84, 3744 (2000)]. Moreover, the PDF approaches this universal form via an interesting mechanism whereby the distribution's negative tail evolves towards form in a different manner than the positive tail.
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http://dx.doi.org/10.1103/PhysRevLett.91.264501 | DOI Listing |
Commun Med (Lond)
January 2025
Rare Disease Translational Center, The Jackson Laboratory, Bar Harbor, ME, USA.
Background: Multiple Sulfatase Deficiency (MSD) is a rare inherited lysosomal storage disorder characterized by loss of function mutations in the SUMF1 gene that manifests as a severe pediatric neurological disease. There are no available targeted therapies for MSD.
Methods: We engineered a viral vector (AAV9/SUMF1) to deliver working copies of the SUMF1 gene and tested the vector in Sumf1 knock out mice that generally display a median lifespan of 10 days.
ISA Trans
January 2025
Department of Applied Mathematics, Bharathiar University, Coimbatore 641046, India; Department of Mathematics, Sungkyunkwan University, Suwon 440746, Republic of Korea. Electronic address:
This work describes the dissipative constraint-based load frequency control problem for multi-area power system under load disturbances. Particularly, a new model incorporating time-varying delays and cyber-attacks are widespread in communication networks, significantly impacting control and stability. Consequently, the state-space equations of the addressed model are formulated and analyzed under the impact of false data injection attacks, and time-varying delays.
View Article and Find Full Text PDFIntroduction: In recent years, intravitreal injections (IVT) of vascular endothelial growth factor (VEGF) inhibitors have become the standard of care for several macular disorders. Frequently, the therapeutic course requires numerous injections, posing a burden on patients. Non-adherence to treatment may result in reduced visual outcomes, therefore understanding and addressing the underlying causes is imperative.
View Article and Find Full Text PDFMicrobiol Spectr
January 2025
School of Public Health, the Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang, Guizhou, China.
Unlabelled: Backed by advancements in technologies like microbial sequencing, many studies indicate that the vaginal microbiome is a key marker of female reproductive health. However, further studies are still needed to investigate the correlation between vaginal microbiota (VMB) and outcomes of assisted reproductive technology (ART). Therefore, this study compared the VMB of two types of infertile women undergoing fertilization (IVF) with normal control women during the implantation window period and investigated the effects of VMB characteristics on IVF outcomes.
View Article and Find Full Text PDFUnlabelled: Motivated behaviors are regulated by distributed forebrain networks. Traditional approaches have often focused on individual brain regions and connections that do not capture the topographic organization of forebrain connectivity. We performed co-injections of anterograde and retrograde tract tracers in rats to provide novel high-spatial resolution evidence of topographic connections that elaborate a previously identified closed-loop forebrain circuit implicated in affective and motivational processes.
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