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Transjugular transcatheter edge-to-edge mitral valve repair in a patient with functional mitral regurgitation: a case report.
Eur Heart J Case Rep
January 2025
Department of Cardiovascular Medicine, Sendai Kousei Hospital, 1-20 Tsutsumidori-amamiya, Aoba Ward, Sendai, Miyagi 9810914, Japan.
Article Synopsis
- The transcatheter edge-to-edge mitral valve repair (M-TEER) using the MitraClip system is usually done via the transfemoral approach, but the transjugular approach can be a viable alternative when the former isn't possible.
- A 57-year-old man with heart failure and severe functional mitral regurgitation could not undergo the transfemoral approach due to an occluded inferior vena cava, leading to the decision to use the transjugular technique instead.
- The procedure was successful with no complications, significantly reducing the patient's mitral regurgitation, and he showed sustained improvement a year later.
AGA Clinical Practice Update on Management of Portal Vein Thrombosis in Patients With Cirrhosis: Expert Review.
Gastroenterology
December 2024
Division of Gastroenterology and Hepatology, Department of Medicine, Endeavor Health, Chicago, Illinois.
Description: Portal vein thromboses (PVTs) are common in patients with cirrhosis and are associated with advanced portal hypertension and mortality. The treatment of PVTs remains a clinical challenge due to limited evidence and competing risks of PVT-associated complications vs bleeding risk of anticoagulation. Significant heterogeneity in PVT phenotype based on anatomic, host, and disease characteristics, and an emerging spectrum of therapeutic options further complicate PVT management.
View Article and Find Full Text PDFThe Role of Vitamin D Deficiency in Hepatic Encephalopathy: A Review of Pathophysiology, Clinical Outcomes, and Therapeutic Potential.
Nutrients
November 2024
Department of Radiology, Louisiana State University Health Sciences Center-Shreveport, 1501 Kings Highway, Shreveport, LA 71103, USA.
Hepatic encephalopathy (HE) is a neuropsychiatric condition frequently associated with cirrhosis and portosystemic shunting (PSS). It imposes a significant clinical and economic burden, with increasing attention toward identifying modifiable factors that could improve outcomes. Emerging evidence suggests that vitamin D deficiency (VDD), prevalent in patients with cirrhosis, may contribute to the development and severity of HE.
View Article and Find Full Text PDFInsights and future directions in studying intestinal microbiota post-transjugular intrahepatic portosystemic shunt for hepatitis B virus-related portal hypertension.
World J Gastroenterol
December 2024
Department of Traditional Chinese Medicine, Peking University Third Hospital, Beijing 100191, China.
The gut microbiota (GM) plays a major role in the progression and treatment response of liver diseases, with diverse compositions based on different etiologies. In China, hepatitis B virus (HBV) infection is the leading cause of cirrhosis and affects the GM composition in patients with cirrhosis-related portal hypertension (PH). However, a few studies have been conducted on GM alterations after transjugular intrahepatic portosystemic shunt (TIPS) in patients with HBV-related PH.
View Article and Find Full Text PDFRecent TIPS increases postoperative mortality: A national cohort study.
Hepatol Commun
December 2024
Department of Medicine, Division of Gastroenterology and Hepatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Article Synopsis
- Patients with cirrhosis have a higher risk of dying after surgery, often due to complications from portal hypertension, and some believe preoperative TIPS (transjugular intrahepatic portosystemic shunt) placement might help reduce this risk.
- A study analyzed data from Veterans Health Administration patients who had major surgery between 2008-2022, comparing outcomes between those who had TIPS placed within 6 months of surgery and those who did not.
- Results showed that TIPS placement was linked to a significantly higher risk of postoperative mortality and indicated poorer liver function right before surgery, suggesting that TIPS may not be beneficial for all patients with cirrhosis undergoing surgery.
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