The authors analysed 242 clinical cases of open and closed injury to the colon and the results of experiments on 120 animals. Incompetence of the sutures of the colon was encountered in 12 (4.9%) patients: in 10 (5.2%) with punctured-incised injuries, in one (3.3%) with subcutaneous rupture, and in one (5.5%) with gunshot injury. Clinico-experimental studies allowed 2 groups of pathogenetic factors (predisposing and resolving) in the development of incompetence of colonic sutures to be distinguished. The pathogenetic approach forms the basis of the developed complex program of the prevention of incompetence of the sutures of the colon in its injuries. Introduction of the suggested program into clinical practice made it possible to reduce the incidence of incompetence of colonic sutures from 6.6 to 2.0%.

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