The pharmacokinetics of moxifloxacin was studied in 17 mechanically ventilated patients with pneumonia. Patients were given 400 mg of moxifloxacin intravenously. Blood samples and bronchial secretions were taken on days 1 and 4. A dose of 400 mg of moxifloxacin allows one to achieve efficient concentrations in bronchial secretions and plasma.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC321546 | PMC |
http://dx.doi.org/10.1128/AAC.48.2.638-640.2004 | DOI Listing |
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