Synthesis of an S-linked glycopeptide analog derived from human Tamm-Horsfall glycoprotein.

Org Biomol Chem

Fachbereich Chemie, Universität Konstanz, Fach M 725, D-78457 Konstanz, Germany.

Published: January 2004

Direct base catalyzed S-glycosylation of a cysteine and a homocysteine containing peptide with O-acetyl protected bromides in DMF-water solution furnished two glycopeptide fragments. The two glycopeptide fragments were linked to the target glycopeptide with two S-glycosyl residues mimicking a part of Tamm-Horsfall glycoprotein.

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http://dx.doi.org/10.1039/b311583fDOI Listing

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