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Effects of Tongluo Zhitong formula on synovial fibroblast proliferation in human knee osteoarthritis.
Heliyon
January 2025
Department of Orthopedics, Beijing LongFu Hospital, Beijing, China.
Objective: We aimed to investigate the effects of Tongluo Zhitong formula on synovial fibroblast proliferation in human knee osteoarthritis (KOA).
Methods: Discarded synovial tissue collected from patients undergoing total knee arthroplasty at our hospital was digested with type I collagenase. Primary culture was performed on three to four generations of fibroblasts, which were treated with high, medium, and low concentrations of Tongluo Zhitong formula.
State-level actions targeting unethical substance use disorder treatment practices: A qualitative study.
J Subst Use Addict Treat
December 2024
Department of Health Law, Policy & Management, Boston University School of Public Health, Boston, MA, United States of America; Partnered Evidence-based Policy Resource Center, Boston VA Healthcare System, Boston, MA, United States of America; Center for Surgery and Public Health, Brigham and Women's Hospital, Boston, MA, United States of America. Electronic address:
Introduction: There has been increasing recognition of unethical practices occurring in substance use disorder (SUD) treatment, such as patient brokering and deceptive marketing. We conducted a qualitative study with key informants to characterize state actions that have been undertaken to target unethical practices and the context surrounding state-level actions, including barriers and facilitators to their implementation.
Methods: We recruited key informants at the state-level, as well as those from national organizations engaged in improving SUD treatment quality, who could provide perspectives on the scope of unethical practices in the field and ways in which states have sought to prevent unethical practices and improve the quality of SUD treatment.
As a result of the "publish or perish" environment for biomedical journal authors, as well as new developments in open access publication models ("pay to publish") and rapid improvements in artificial intelligence large language models (AI LLMs; e.g., ChatGPT), troubling trends and a propensity for ethical violations now exist.
View Article and Find Full Text PDFOpinion of Polish doctors on the use of futile therapy.
Eur J Public Health
December 2024
Department of Anesthesiology and Intensive Therapy, Silesian Centre for Heart Diseases in Zabrze, Medical University of Silesia, Zabrze, Poland.
The discontinuation of futile therapy is increasingly discussed in Polish clinical practice. Given the need to ensure patient well-being, it is essential to consider whether all clinical options resulting from medical progress should be used for every patient and on what grounds decisions to limit therapy should be based. The aim of our study was to determine the opinions of Polish medical doctors on this topic.
View Article and Find Full Text PDFSearching for private patient information in Internet resources (patient-targeted Google)-experiences of nurses and nursing students.
BMC Nurs
December 2024
Department of Surgical Nursing, Inistitute of Nursing and Midwifery, Jagiellonian University Collegium Medicum, Cracow, Poland.
Background: The Internet is a source of many information about users who are unaware of the extent to which their privacy and anonymity are abolished. The purpose of this study was to evaluate the prevalence of patient-targeted Google and to know about selected factors influencing such searches among nurses and midwives, as well as nursing and midwifery students.
Methods: The study was conducted using a diagnostic survey method and the research tool was an author's survey questionnaire that included a sociodemographic section, questions on patient-targeted Google, and a description of three cases written for the study representing the behavior of members of the therapeutic team in specific situations related to the provision of health services asking respondents to evaluate the actions taken.
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