The results of treatment of 573 patients, operated on the clinic for the period from 1981 to 2000 year for perforative gastroduodenal ulcer were analyzed. In 24 (4.2%) of them the necessity of relaparotomy performance for peritonitis, polyorgan insufficiency had occurred. In all patients complex intensive therapy, intestinal decompression, flowing peritoneal dialysis were conducted, in 10--the governed laparotomy. In 9 patients plasmapheresis was performed, in 8--drainage of ductus thoracicus with lymphosorption, in 7--xenosorption. Application of complex treatment equally with active detoxication in patients with peritonitis, polyorgan insufficiency have allowed to achieve recovery in 66.6% of them.
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