Objectives: To examine whether psychological factors are risk factors for the development of stroke in elderly diabetic patients.

Design: Prospective cohort study.

Setting: Outpatient clinic.

Participants: Three hundred seventy-six diabetic outpatients free of stroke; mean age 75.

Methods: Well-being and diabetes-specific burden were assessed at baseline using the Philadelphia Geriatric Center morale scale and the Elderly Diabetes Burden Scale (EDBS), respectively. Symptomatic stroke was defined as a focal neurological deficit with rapid onset that persists for more than 24 hours, supported by brain computed tomography or magnetic resonance imaging.

Results: During the 3-year follow-up period, 25 symptomatic strokes (24 ischemic strokes and 1 cerebral hemorrhage) occurred. Low scores on the morale scale (
Conclusion: Low well-being and symptom burden were predictors of stroke in elderly patients with diabetes mellitus (DM), although the causal relationship remains unknown.

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http://dx.doi.org/10.1111/j.1532-5415.2004.52055.xDOI Listing

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