To address some of the shortcomings to providing timely and convenient education and support to patients with COPD, especially in the management of dyspnea, the Internet was considered a viable medium to deliver a previously tested program at a distance to reach more patients. Older COPD patients were able to participate in the program and most were very satisfied with the program. Changes were noted in dyspnea, support, self-efficacy, and exercise.
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J Eval Clin Pract
February 2025
Instituto Mexicano del Seguro Social, IMSS Hospital General de Zona Número 17, Monterrey, Nuevo León, México.
Introduction: Rheumatoid arthritis (RA) is a progressive autoimmune inflammatory disease. According to the European League Against Rheumatism (EULAR), the stages of RA progression include pre-RA, preclinical RA, inflammatory arthralgia, arthralgia with positive antibodies, arthralgia suspected of progressing to RA, undifferentiated arthritis and finally established RA. According to the Community Oriented Program for Control of Rheumatic Diseases (COPCORD), the prevalence of RA in Mexico is 1.
View Article and Find Full Text PDFBehav Res Methods
December 2024
Department of Psychology, Bielefeld University, Universitätsstraße 25, 33615, Bielefeld, Germany.
Following the (revised) latent state-trait theory, the present study investigates the within-subject reliability, occasion specificity, common consistency, and construct validity of cognitive control measures in an intensive longitudinal design. These indices were calculated applying dynamic structural equation modeling while accounting for autoregressive effects and trait change. In two studies, participants completed two cognitive control tasks (Stroop and go/no-go) and answered questions about goal pursuit, self-control, executive functions, and situational aspects, multiple times per day.
View Article and Find Full Text PDFSci Rep
December 2024
Affiliated Hospital of Jiangnan University, Wuxi, 214000, Jiangsu, China.
Vitamin D is crucial for maintaining bone health and development, and bone mineral accumulation during childhood and adolescence affects long-term bone health. Vitamin D deficiency has been widely recognized as one of the main causes of osteoporosis and fractures, especially during the growth and development stage of children. Recent studies have shown that vitamin D deficiency may affect the deviation of bone development in children by mediating lipid metabolism disorders, but its specific mechanism of action has not been fully elucidated.
View Article and Find Full Text PDFSci Rep
December 2024
Department of Physics, University of Trento, Via Sommarive 14, 38123, Povo (TN), Italy.
It has been argued that realistic models of (singularity-free) black holes (BHs) embedded within an expanding Universe are coupled to the large-scale cosmological dynamics, with striking consequences, including pure cosmological growth of BH masses. In this pilot study, we examine the consequences of this growth for the stochastic gravitational wave background (SGWB) produced by inspiraling supermassive cosmologically coupled BHs. We show that the predicted SGWB amplitude is enhanced relative to the standard uncoupled case, while maintaining the [Formula: see text] frequency scaling of the spectral energy density.
View Article and Find Full Text PDFJ Thorac Oncol
December 2024
Division of Medical Oncology, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Republic of Korea. Electronic address:
Introduction: Treatment with adjuvant osimertinib for three years is the standard-of-care for resected stage IB-IIIA non-small cell lung cancer (NSCLC) harboring epidermal growth factor receptor (EGFR)-mutations. The role of neoadjuvant osimertinib in the perioperative setting is yet to be elucidated in the NeoADAURA study (NCT04351555).
Methods: This is a single center, pilot study of patients with clinical stage IA-IIIA NSCLC (AJCC 8th edition) harboring an activating EGFR mutation (Exon 19 deletion, L858R) (NCT04816838).
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