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Case report: Dirofilarial infection of the face.

IDCases

January 2025

Division of Infectious Diseases and Tropical Medicine, Department of Medicine I, Leipzig University Medical Center, Leipzig, Germany.

An 18-year-old male patient from Ukraine, living in Germany for 2 years, presented with a painless subcutaneous swelling on the left cheek that had been present for several months. Finally, the diagnosis of subcutaneous dirofilariasis caused by was confirmed by 12S rRNA gene PCR and sequencing from tissue by nematode-specific PCRs followed by sequencing after surgical resection of the lesion. Microfilaremia was ruled out and no further treatment was required.

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Background: Dirofilaria immitis and D. repens are mosquito-borne filaroids that primarily infect dogs but also cats. Diagnosing feline dirofilariosis is challenging because of the low parasitic burdens and transient or absent microfilaremia.

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Article Synopsis
  • Dirofilariosis is a parasite disease caused by Dirofilaria species, mainly affecting wild carnivores and raising concerns about animal health and potential transmission to domestic dogs and humans.
  • In a study in Croatia, researchers examined wild carnivores, finding D. immitis in 6.5% of golden jackals, but none in red foxes or European badgers.
  • Infected jackals showed varying parasite loads and possible health impacts, highlighting the need for further research on their role as potential infection reservoirs for other species.
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Zoonotic Dirofilaria sp. "hongkongensis" in subcutaneous nodules from dogs and cats, Hong Kong SAR.

Parasit Vectors

November 2024

Department of Veterinary Clinical Sciences, Jockey Club College of Veterinary Medicine and Life Sciences, City University of Hong Kong, Kowloon Tong, Hong Kong SAR, China.

Background: Dirofilaria sp. "hongkongensis" is a putative Dirofilaria species, initially identified in subcutaneous nodules in humans in Hong Kong and in other South and Southeast Asian regions. While it differs genetically from the better-known zoonotic species, Dirofilaria repens and Dirofilaria immitis, information on the lesions caused by Dirofilaria sp.

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"Human dirofilariasis, caused by filarial worms of the genus , is considered an emerging zoonotic filarial infection transmitted to humans by zoo-anthropophilic blood-sucking insects. The most common species causing human infections include and . In this case report, we present the case of a 60-year-old male patient who reported the presence of an intraoral swelling in the right maxillary vestibular region.

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