The antibacterial and antifungal action of saponins Sx1, taurozide H2, taurozide I and their effect on bioluminescent system of photobacteria Photobacterium phosphoreum (Cohn) Ford were investigated. Saponins H2 and I had no antimicrobial effect. Saponin Sx1 possessed antifungal activity in vitro with respect to Candida albicans, C. krusei, C. tropicalis. Saponin Sx1 is less toxic to P. phosphoreum than well-known antiseptics--chlorhexedin and miramistin.
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Vopr Virusol
June 2018
Medical Academy named after S.I. Georgievsky, Federal State Autonomous Educational Institution of Higher Education «V. I. Vernadsky Crimean Federal University».
Triterpene saponin Taurosid Sx1 purified from leaves of the plant Crimean Ivy Hedera taurica Carr. (Araliaceae) was evaluated for its cytotoxic activity against lymphoblastoid cell lines MT-4, Jurkat-tat, U937, and human peripheral blood monocytes. The ability of saponin to influence HIV-1 replication was studied as well.
View Article and Find Full Text PDFThe antibacterial and antifungal action of saponins Sx1, taurozide H2, taurozide I and their effect on bioluminescent system of photobacteria Photobacterium phosphoreum (Cohn) Ford were investigated. Saponins H2 and I had no antimicrobial effect. Saponin Sx1 possessed antifungal activity in vitro with respect to Candida albicans, C.
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