[Plasma levels of ascorbic acid and vitamin E in patients with liver cirrhosis].

Zhejiang Da Xue Xue Bao Yi Xue Ban

The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, China.

Published: December 2003

AI Article Synopsis

  • - The study aimed to evaluate plasma levels of ascorbic acid (vitamin C) and vitamin E in patients with liver cirrhosis and their importance.
  • - Plasma levels of ascorbic acid, vitamin E, and lipoperoxides were significantly lower in cirrhosis patients compared to healthy individuals.
  • - The findings suggest that liver cirrhosis leads to decreased levels of these vitamins, indicating a disruption in the body’s oxidative and antioxidative balance.

Article Abstract

Objective: To investigate the plasma levels of ascorbic acid and vitamin E in patients with liver cirrhosis and to explore their significance.

Methods: The plasma levels of ascorbic acid,vitamin E and lipoperoxides in patients with liver cirrhosis were measured, and the results were compared with those of sex-and age-matched healthy subjects.

Result: The plasma levels of ascorbic acid, vitamin E and lipoperoxides in the patients group were (42.94 +/-6.99)micromol/L, (17.99 +/-3.51)micromol/L and (14.09 +/-1.28)micromol/L, respectively, while those in the control group were (53.30 +/-9.45)micromol/L (t=9.50, P=0.000), (24.59 +/-7.22)micromol/L (t=7.94, P=0.000) and (12.11 +/-1.20)micromol/L (t=17.21, P=0.000), respectively.

Conclusion: The levels of ascorbic acid and vitamin E in patients with liver cirrhosis decrease significantly,which may indicates the disturbance of balance between oxidation and antioxidation.

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Source
http://dx.doi.org/10.3785/j.issn.1008-9292.2003.06.016DOI Listing

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