No doubt, schistosomiasis tops all the endemic parasitic diseases world-wide particularly in Egypt. This study evaluated the efficacy of Mirazid (Commiphora molmol) in the treatment of parasitologically and clinically and ultrasonography confirmed cases of schistosomiasis haematobium in Tatoon village. A sum of 70 out of 885 individuals of both sexes (>15 to 60 years old) screened for S. haematobium infection were selected. They had light infection (1-10 eggs/10 ml.), moderate infection (10-100 eggs/10 ml.) and heavy infection (>100/10 ml.). They were subjected to urine and stool analysis, renal function tests, clinical examination and abdomino-pelvic ultrasound. They were treated with Mirazid as 10 mgm/Kg. However, eight of them were unable to swallow the drug. Out of the 62 schistosomiasis haematobium patients, 57 (91.9%) were cured after two months follow up and the cure rate reached 59 (95.2%) on the 3rd month post-Mirazid treatment. The cure result was evaluated clinically, parasitologically and ultrasonographically. So, Mirazid in a dose of two capsules (600 mgm) on an empty stomach before breakfast for six successive days proved to be very effective and safe in the treatment of schistosomiasis haematobium.

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