Parallel imaging applied to first-pass, contrast-enhanced cardiac MR can yield greater spatial coverage for a fixed temporal resolution. The method combines rate R=2 acceleration using TSENSE with shot-to-shot interleaving of two slices. The square root R SNR loss is largely compensated for by a longer effective repetition time (TR) and increased flip angle associated with slice interleaving. In this manner, increased spatial coverage is achieved while comparable or better image quality is maintained. Single-heartbeat temporal resolution was accomplished with spatial coverage of eight slices at heart rates up to 71 bpm, six slices up to 95 bpm, and four slices up to 143 bpm. Experiments in normal subjects (N=6) were performed to assess signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) values.
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http://dx.doi.org/10.1002/mrm.10663 | DOI Listing |
Sci Total Environ
January 2025
Ministry of Earth Science, New Delhi 110003, India.
Glaciers of Jammu and Kashmir are retreating faster than those in the broader northwestern Himalayas, yet some glaciers in the Chenab River basin display signs of periodic advancement and mass gain (2005-2007). These features, such as coalescing lobate structures and blocked meltwater streams, raise intriguing questions about localized glacier dynamics. While global concerns over climate change and glacier retreat persist, the lack of detailed evidence regarding glacier advance in this region warrants further investigation.
View Article and Find Full Text PDFHeliyon
January 2025
Guangzhou Xinhua University, School of Resources and Planning, Guangzhou, 510520, China.
Emergency shelters are multifunctional spaces that provide safe refuge, essential life protection, and rescue command for residents in case of urban disaster. These shelters constitute crucial components of urban public safety. This study, with Tianhe District in Guangzhou City as a case study, used data from emergency evacuation sites and other socio-economic sources to construct an evaluation system for spatial suitability evaluation and layout optimization of emergency shelters.
View Article and Find Full Text PDFBMJ Open
December 2024
Division of Research, Kaiser Permanente, Pleasanton, California, USA.
Objectives: The US Preventive Services Task Force recommends screening of adults aged 35-70 with a body mass index ≥25 kg/m for type 2 diabetes and referral of individuals who screen positive for pre-diabetes to evidence-based prevention strategies. The diabetes burden in the USA is predicted to triple by 2060 necessitating strategic diabetes prevention efforts, particularly in areas of highest need. This study aimed to identify pre-diabetes hotspots using geospatial mapping to inform targeted diabetes prevention strategies.
View Article and Find Full Text PDFNat Commun
January 2025
Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, 99354, USA.
With advanced mass spectrometry (MS)-based proteomics, genome-scale proteome coverage can be achieved from bulk tissues. However, such bulk measurement lacks spatial resolution and obscures tissue heterogeneity, precluding proteome mapping of tissue microenvironment. Here we report an integrated wet collection of single microscale tissue voxels and Surfactant-assisted One-Pot voxel processing method termed wcSOP for robust label-free single voxel proteomics.
View Article and Find Full Text PDFBMC Cancer
January 2025
Department of Community & Family Medicine, All India Institute of Medical Sciences, 151001, Bathinda, Punjab, India.
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