Objective: To investigate the presence of HPV infection of oral mucosa proliferative lesions in children and determine the associations of HPV types with oral mucosa lesions in children.
Methods: Immunohistochemical method and in situ hybridization techniques were applied to detect human papillomavirus (HPV) infection in biopsies taken from clinical lesions in oral mucosa of 30 children.
Results: The most frequent lesions detected were SCP (66.7%), followed by CA and FEH. The HPV viral antigen was present in 73.3% (22/30) of the oral benign epithelial proliferative lesions in children. A high frequency HPV was found in CA (6/6) and SCP (15/20) by means of IHC. In the ISH positive case, high risk HPV 16/18 was observed in 77.3% (17/22).
Conclusion: This study demonstrates a high prevalence of HPV infection in children's oral mucosa proliferative lesions, and high-risk HPV16/18 are predominant in children's oral mucosa proliferative lesions.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Exploring the role of the MUC1 mucin in human oral lubrication by tribological in vitro studies.
Sci Rep
December 2024
Ecole Centrale de Lyon, CNRS, ENTPE, LTDS, Ecully, UMR5513, 69130, France.
In the context of the oral cavity, an organic layer known as the mucosal pellicle (MP) adheres to the surface of the oral epithelium, playing a pivotal role in lubricating and safeguarding oral tissues. The formation of the MP is driven by interactions between a transmembrane mucin known as MUC1, located on the oral epithelium, and salivary secreted mucin, namely MUC5B and MUC7. This study aimed to investigate the function of MUC1 and the influence of its structure on MP lubrication properties.
View Article and Find Full Text PDFMucoepidermoid Carcinoma: Enhancing Diagnostic Accuracy and Treatment Strategy through Machine Learning Models and Web-Based Prognostic Tool.
J Stomatol Oral Maxillofac Surg
December 2024
Faculty of Medicine, Jordan University of Science & Technology, Irbid, Jordan. Electronic address:
Background: Oral cancer, particularly mucoepidermoid carcinoma (MEC), presents diagnostic challenges due to its histological diversity and rarity. This study aimed to develop machine learning (ML) models to predict survival outcomes for MEC patients and pioneer a clinically accessible prognostic tool.
Methods: Using the SEER database (2000-2020), we constructed predictive models with five ML algorithms: Random Forest Classifier (RFC), Gradient Boosting Classifier (GBC), Logistic Regression (LR), K-Nearest Neighbors (KNN), and Multilayer Perceptron (MLP).
Oral colon-retentive inulin gels protect against radiation-induced hematopoietic and gastrointestinal injury by improving gut homeostasis.
Int J Biol Macromol
December 2024
Beijing Institute of Radiation Medicine, Beijing 100850, China. Electronic address:
Ionizing radiation-induced injury often occurs in nuclear accidents or large-dose radiotherapy, leading to acute radiation syndromes characterized by hematopoietic and gastrointestinal injuries even to death. However, current radioprotective drugs are only used in hospitals with unavoidable side effects. Here, we heated the aqueous solution of inulin, a polysaccharide dietary fiber, forming colon-retentive gel as a radiation protector in radiotherapy.
View Article and Find Full Text PDFDesign, additive manufacturing, and characterization of an organ-on-chip microfluidic device for oral mucosa analogue growth.
J Mech Behav Biomed Mater
December 2024
Department of Prosthodontics, Dental and Craniofacial Bioengineering and Applied Biomaterials, School of Dentistry, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, 54124, Greece. Electronic address:
Introduction: Α customized organ-on-a-chip microfluidic device was developed for dynamic culture of oral mucosa equivalents (Oral_mucosa_chip-OMC).
Materials And Methods: Additive Manufacturing (AM) was performed via stereolithography (SLA) printing. The dimensional accuracy was evaluated via microfocus computed tomography (mCT), the surface characteristics via scanning electron microscopy (SEM), while the mechanical properties via nanoindentation and compression tests.
The Preliminary Results of a Modified Von Langenbeck Cleft Palate Repair With Tension-free Mucoperiosteal Flap Near Nasal Cavity Without Relaxation Incision.
J Craniofac Surg
December 2024
Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, & People's Hospital of Morin Dawa Daur Autonomous Banner, Inner Mongolia Autonomous Region, People's Republic of China.
To explore the application of modified Von Langenbeck cleft palate repair with tension-free mucoperiosteal flap near the nasal cavity and without relaxation incision, and the cleft palate defect was repaired by covering both sides of the edge of the in situ mucoperiosteal flap. This treatment method provides a good aesthetic restoration effect. Modified Von Langenbeck cleft palate repair with mucoperiosteal flap near the nasal cavity without tension and relaxation incision was used to repair the cleft palate.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!