Birdshot retinochoroidopathy is a rare, chronic, bilateral, posterior uveitis with a distinctive clinical presentation and a strong genetic association. Middle aged white people of northern European extraction are most commonly. The pathogenesis is unknown, but HLA-A29 positivity appears to confer predisposition and retinal autoimmunity seems to play a role. Clinically, there are patches of postequatorial choroidal and retinal pigment epithelial depigmentation, vitreal cells, macular and disc edema, and venous sheathing. This review provides an updated summary of the current state of knowledge about birdshot retinochoroidopathy. It includes results of visual field and electrophysiological tests.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Spectrum of Imaging Characteristics of Birdshot Chorioretinopathy.
Ocul Immunol Inflamm
January 2025
Department of Ophthalmology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Birdshot chorioretinopathy (BSCR) is a bilateral, chronic posterior uveitis with characteristic clinical and imaging findings. Multimodal imaging including optical coherence tomography, fluorescein, and indocyanine green angiography is useful in diagnosis, as well as monitoring disease activity. Cystoid macular edema, choroidal thickening and infiltration, ellipsoid loss, and vasculitis are important imaging markers for disease activity.
View Article and Find Full Text PDFAn update of multimodal imaging in white dot syndrome.
Oman J Ophthalmol
October 2024
Department of Uvea, Sankara Nethralaya, Chennai, Tamil Nadu, India.
The white dot syndromes are a group of phenotypically similar disorders characterized by multiple lesions at the level of the outer retina, retinal pigment epithelium, and choroid. Common white dot syndromes whose imaging modalities have been described in this article are multiple evanescent white dot syndrome, acute posterior multifocal placoid pigment epitheliopathy, acute zonal occult outer retinopathy, multifocal choroiditis and panuveitis, punctate inner choroidopathy, serpiginous choroiditis, and birdshot chorioretinopathy. The various imaging modalities help us to better understand the pathophysiology of the various entities and help in diagnosing, monitoring, and prognosticating them.
View Article and Find Full Text PDFIndolent Nonprogressive Multifocal Choroidal Lesions: A Review of Literature and Case Report Based on Similarity.
Ocul Immunol Inflamm
December 2024
School of Medicine, Dentistry and Biomedical Sciences, Queens Belfast University, Belfast, UK.
Purpose: To present a case of indolent, nonprogressive multifocal choroidal lesions and contribute to the limited reports aiding this diagnosis, supplemented by a review of the literature.
Methods: Clinical records of a patient were reviewed alongside relevant literature from PubMed, Cochrane, and Google Scholar.
Results: A male in late 50s presented with a 10-year history of unilateral yellow-white asymptomatic fundus lesions in the left eye.
The Impact of HLA-A29 Homozygosity and of the Second HLA-A Allele on Susceptibility and Severity of Birdshot Chorioretinitis.
Invest Ophthalmol Vis Sci
November 2024
Université Paris Cité, Centre d'ophtalmologie de l'Assistance Publique, Hôpitaux de Paris, Paris, France.
Purpose: HLA-A29 is the main susceptibility factor for birdshot chorioretinitis (BSCR). Our study assessed the impact of the second HLA-A allele alongside HLA-A29 on BSCR severity and susceptibility, focusing on HLA-A29 homozygous patients and those with alleles from the HLA-Aw19 group.
Methods: We included 120 additional cases to our previous analysis of 286 patients with BSCR, all HLA-A29 positive.
CYSTOID MACULAR EDEMA IN BIRDSHOT RETINOCHOROÏDITIS: Long-Term Treatment Study in 142 Patients.
Retina
October 2024
Department of Ophthalmology, Reference Center for Rare Diseases, Pitié-Salpêtrière Hospital, Paris-Sorbonne University, Paris, France.
Purpose: To assess the long-term efficacy and safety of treatments for cystoid macular edema in birdshot retinochoroïditis.
Methods: Observational retrospective study of 142 HLA-A29-positive patients with cystoid macular edema; the main outcome was the optical coherence tomography intraretinal cysts resolution.
Results: During the mean follow-up of 75 months (12-178), 61.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!