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A Global Collaborative Comparison of SARS-CoV-2 Antigenicity Across 15 Laboratories.
Viruses
December 2024
World Health Organization, 1202 Geneva, Switzerland.
Setting up a global SARS-CoV-2 surveillance system requires an understanding of how virus isolation and propagation practices, use of animal or human sera, and different neutralisation assay platforms influence assessment of SARS-CoV-2 antigenicity. In this study, with the contribution of 15 independent laboratories across all WHO regions, we carried out a controlled analysis of neutralisation assay platforms using the first WHO International Standard for antibodies to SARS-CoV-2 variants of concern (source: NIBSC). Live virus isolates (source: WHO BioHub or individual labs) or spike plasmids (individual labs) for pseudovirus production were used to perform neutralisation assays using the same serum panels.
View Article and Find Full Text PDFAdvantages of Broad-Spectrum Influenza mRNA Vaccines and Their Impact on Pulmonary Influenza.
Vaccines (Basel)
December 2024
Division of HIV/AIDS and Sex-Transmitted Virus Vaccines, National Institutes for Food and Drug Control (NIFDC), Beijing 102629, China.
Influenza poses a significant global health challenge due to its rapid mutation and antigenic variability, which often leads to seasonal epidemics and frequent outbreaks. Traditional vaccines struggle to offer comprehensive protection because of mismatches with circulating viral strains. The development of a broad-spectrum vaccine is therefore crucial.
View Article and Find Full Text PDFAdvancements in Smart Wearable Mobility Aids for Visual Impairments: A Bibliometric Narrative Review.
Sensors (Basel)
December 2024
Department of Industrial Design, Guangdong University of Technology, Guangzhou 510006, China.
Research into new solutions for wearable assistive devices for the visually impaired is an important area of assistive technology (AT). This plays a crucial role in improving the functionality and independence of the visually impaired, helping them to participate fully in their daily lives and in various community activities. This study presents a bibliometric analysis of the literature published over the last decade on wearable assistive devices for the visually impaired, retrieved from the Web of Science Core Collection (WoSCC) using CiteSpace, to provide an overview of the current state of research, trends, and hotspots in the field.
View Article and Find Full Text PDFSimulation and Assessment of Thermal-Stress Analysis of Welding Materials in IGBT.
Micromachines (Basel)
December 2024
School of Material Science and Engineering, Huazhong University of Science & Technology, Wuhan 430074, China.
Insulated gate bipolar transistors (IGBTs), as an important power semiconductor device, are susceptible to thermal stress, thermal fatigue, and mechanical stresses under high-voltage, high-current, and high-power conditions. Elevated heat dissipation within the module leads to fluctuating rises in temperature that accelerate its own degradation and failure, ultimately causing damage to the module as a whole and posing a threat to operator safety. Through ANSYS Workbench simulation analysis, it is possible to accurately predict the temperature distribution, equivalent stress, and equivalent strain of solder materials under actual working conditions, thus revealing the changing laws of the heat-mechanical interaction in solder materials.
View Article and Find Full Text PDFConstruction of a Molecular Dynamics Model of N-A-S-H Geopolymer Based on XRD Analysis.
Materials (Basel)
December 2024
College of Materials Science and Engineering, Shenyang Jianzhu University, Shenyang 110168, China.
A geopolymer is a low-carbon cementitious material, and its condensation process is akin to the formation of inorganic polymers. The crystal phase of synthesized geopolymers was identified using XRD; the scattering peaks of amorphous phases were analyzed, and the zeolite minerals akin to different n(Si)/n(Al) geopolymers were determined. Based on this, a model structure of N-A-S-H geopolymers was established.
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